Introduction And Importance: Intestinal obstruction is a common surgical emergency encountered almost in every casualty. Though adhesions, hernias and malignancies are the common causes of obstruction, various articles describe unusual causes of intestinal obstruction which needs timely surgical interventions to prevent morbidity and mortality.
Case Presentation: In this case report we present the history of a 50 year old sub-fertile woman who presented with features of intestinal obstruction and confirmed radiologically with both plain x-ray and computed tomography. After conservative management and as the imaging didn't show the cause of obstruction, exploratory laparotomy was performed. There we found have encircling of left fallopian tube around mid-ileum with gangrenous part. Left salphingectomy and bowel resection with side-to-side anastomosis resulted in a favorable outcome.
Clinical Discussion: Intestinal obstruction can compromise blood flow to bowel loops leading to gangrene, perforation and death.
Conclusion: Awareness, early recognition and timely intervention in intestinal obstruction is mandatory to prevent poor outcomes, especially in cases of unknown cause and not responding to conservative management. The real surgical challenge is not the decision whether to perform surgery, but the decision when and how to perform it.
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http://dx.doi.org/10.1016/j.ijscr.2023.108471 | DOI Listing |
Biomaterials
December 2024
Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, 325011, China. Electronic address:
The effective prevention and treatment of anastomotic leakage after intestinal anastomosis for colorectal diseases is still a major clinical challenge. In order to assist intestinal anastomosis healing and avoid anastomotic leakage caused by high tension, low blood supply or infection, we designed a double-layer nanofiber intestinal anastomosis scaffold, which was composed of electrospun PTMC/PHA nanofibers as the main layer, and electrospun PVA/OHA-Gs nanofibers with antibacterial properties as the antibacterial surface layer. This double-layer scaffold has good toughness, its maximum tensile force value could reach 8 N, elongation could reach 400 %, and it has hydrophilic properties, and its contact angle was about 60°.
View Article and Find Full Text PDFSurg Endosc
January 2025
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background And Aims: Self-expandable metal stents (SEMS) are effective in alleviating malignant colorectal obstruction. However, bowel perforation following SEMS placement remains a significant concern, as it can adversely affect oncological outcomes. This study aimed to evaluate the recurrence and overall survival rates associated with SEMS-related bowel perforations.
View Article and Find Full Text PDFCancer Immunol Immunother
January 2025
Department of Medical Oncology, Institut de Cancérologie de L'Ouest, 44805, Saint Herblain, France.
Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
Department of Endocrinology, Odense University Hospital, Odense, Denmark.
Osteogenesis imperfecta (OI) is a group of rare genetic disorders most commonly caused by reduced amount of biologically normal collagen type I, a structural component of the gastrointestinal tract and abdominal wall. The risk of gastrointestinal (GI) disease in individuals with OI is not well understood, despite GI complaints being frequently reported by the OI population. To investigate the risk of GI diseases in individuals with OI.
View Article and Find Full Text PDFJ Inflamm Res
December 2024
Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, People's Republic of China.
The global rise in diabetes mellitus (DM), particularly type 2 diabetes (T2D), has become a major public health challenge. According to the "hygiene hypothesis", helminth infections may offer therapeutic benefits for DM. These infections are known to modulate immune responses, reduce inflammation, and improve insulin sensitivity.
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