Facile In-Situ photocatalytic reduction of AuNPs on multilayer Core-Shell FeO@SiO@PDA magnetic nanostructures and their SERS application.

Surface-enhanced Raman scattering (SERS) is a promising analytical technique for the rapid, sensitive, and repeatable detection in various SERS application fields. Herein, a new type of potential magnetically recyclable SERS substrate was designed and rapidly synthesized via a facile three-step template method. First, the magnetic ferroferric oxide (FeO) cores were prepared by a convenient solvothermal approach, and coated with a thin layer of silica by a sol-gel process in order to improve their stability in complicated environments. Next, the negatively charged polydopamine (PDA)/K[SiWVO]·7HO (PDA/SiWV) outer shell was assembled upon the magnetic FeO@SiO core-shell nanoparticles via a layer-by-layer sequential adsorption process using the stickiness of PDA. The SiWV multilayer shell can be used as the subsequent photocatalytic reduction precursors for the in-situ loading of high-density gold nanoparticles (AuNPs), without any other organic additives. The AuNPs decorated multilayer core-shell FeO@SiO@PDA magnetic nanostructures were employed as a potential magnetically recyclable SERS substrate, and showed excellent SERS performance. Using crystal violet (CV) as a model target, the as-fabricated AuNPs modified multilayer core-shell FeO@SiO@PDA magnetic nanostructures SERS substrates exhibited significant enhancement, and pushed the detection limit down to 10 M. Aside from the ultrahigh sensitivity, these SERS substrates also possess an excellent reproducibility (relative standard deviation (RSD) ∼ 8.3%), long-term stability (75 days), and unique chemical stability capability in different organic solvents and different environments with pH ≤ 10. Furthermore, a real-life application is also performed by the detection of melamine in spiked milk solution using the as-prepared magnetic nanostructures SERS-active substrates (limit of detection (LOD), 10 M). These results highlight that the rational design and controllable synthesis of multifunctional magnetic SERS substrates is a promising strategy in many different application fields such as biosensing, photoelectrocatalysis, and medical diagnosis.