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Disseminated Mycobacterium abscessus infection with idiopathic CD4+ T-lymphocytopenia: a case report and review of the literature.
J Med Case Rep
December 2024
Center for Medical Experiments (CME), Guangming District People's Hospital, Shenzhen, 518106, China.
Background: Idiopathic CD4+ T lymphocytopenia is a rare immune dysfunction disease that is usually found after opportunistic infections. Mycobacterium abscessus is a rapidly growing mycobacterium that can cause pulmonary infections, lymphadenitis, skin and soft tissue infections, disseminated infections, among others, as a conditional pathogenic bacterium.
Case Presentation: We present the case of a 43-year-old Chinese woman who developed disseminated Mycobacterium abscessus infection due to idiopathic CD4+ T lymphocytopenia.
Immune cell infiltration and modulation of the blood-brain barrier in a guinea pig model of tuberculosis: Observations without evidence of bacterial dissemination to the brain.
PLoS One
December 2024
Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is a chronic inflammatory disease. Although typically associated with inflammation of the lungs and other peripheral tissues, increasing evidence has uncovered neurological consequences attributable to Mtb infection. These include deficits in memory and cognition, increased risk for neurodegenerative disease, and progressive neuropathology.
View Article and Find Full Text PDFTuberculous pericarditis in a 71-year-old immunocompetent patient: Case report.
IDCases
November 2024
Doctor of Medicine and Surgery, Hospital Escuela Universitario, Honduras.
Tuberculosis is a transmissible disease caused by the bacterium . It is the leading cause of mortality due to infectious diseases. Tuberculous pericarditis is one of the manifestations of extrapulmonary tuberculosis and represents the primary cause of pericardial effusion in developing countries.
View Article and Find Full Text PDFThe value of metagenomic next-generation sequencing with blood samples for the diagnosis of disseminated tuberculosis.
Front Cell Infect Microbiol
December 2024
Department of Infectious Diseases, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Objective: The aim of this study was to assess the clinical value of metagenomic next-generation sequencing (mNGS) of blood samples for the identification of disseminated tuberculosis (DTB).
Methods: A total of 48 individuals suspected of DTB were enrolled. All patients underwent mNGS of peripheral blood and conventional microbiological tests.
Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat.
Aust Vet J
December 2024
Centre for Veterinary Education, The University of Sydney, Sydney, Australia.
In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the "leprosy-like" diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp. or widely disseminated granulomatous disease, which is usually caused by members of the Mycobacterium avium-intracellulare complex (MAC). Disseminated MAC disease is rare, but when it occurs, usually develops in immunocompromised hosts with defective cell-mediated immunity.
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