A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts.

Yu Ishimoto Luis F Menezes Fang Zhou Teruhiko Yoshida Taishi Komori Jiahe Qiu Marian F Young Huiyan Lu Svetlana Potapova Patricia Outeda Terry Watnick Gregory G Germino

Kidney Int

Polycystic Kidney Disease Section, Kidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, USA. Electronic address:

Published: September 2023

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529617	PMC
http://dx.doi.org/10.1016/j.kint.2023.05.027	DOI Listing

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