Background: It was reported that pseudoexfoliative material deteriorates iris, brain, heart and lung functions. This material is also found in the skin.
Aims: The purpose of this study was to investigate the possible effects of pseudoexfoliation material on the aging of the facial skin.
Study Design: Cross-sectional study.
Methods: Forty pseudoexfoliation syndrome (PES) cases and 40 age- and gender-matched controls were evaluated. Job, cigarette use and the presence of any systemic diseases as well as the duration of sun exposure for all the cases were recorded. All of the cases underwent facial skin examination with Wrinkle Assessment Scale as per Lemperle G et al. and Pinch Test.
Results: Wrinkle Assessment Scale scores of the groups also were compared for all 8 facial locations. There were statistically significant differences found between Wrinkle Assessment Scale scores in PES and Control Group for all 8 locations. Mean Wrinkle Assessment Scale scores of women were 4.12 ± 0.74 in Control Group and 4.75 ± 0.37 in PES group (p = 0.0001). For men, mean Wrinkle Assessment Scale scores were 3.77 ± 0.72 in Control group and 4.54 ± 0.36 in PES group (p = 0.002).
Conclusion: These results implies that there is quicker progression in aging of facial skin in PES than normals.
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http://dx.doi.org/10.1080/15569527.2023.2234024 | DOI Listing |
J Cosmet Dermatol
January 2025
Queen's Medical Research Institute, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Background: Coenzyme Q10 (CoQ10) is widely recognized for its powerful antioxidant properties, sparking considerable interest in its application within skincare treatments. However, its inherently poor water solubility has posed a major challenge in formulating effective skincare products.
Methods: This research aimed to develop and evaluate a water-soluble CoQ10 serum by forming a complex with hydroxypropyl β-cyclodextrin (HPβCD).
Food Chem
December 2024
Key Laboratory of Green Processing and Intelligent Manufacturing of Lingnan Specialty Food of Ministry and Rural Affairs, College of Light Industry and Food, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. Electronic address:
'Tuogu' and 'Bingtang' plums display unique textural responses to salt curing, manifesting in volume reduction, surface wrinkling, and alterations in color and texture, alongside ongoing material exchange. Over a seven-day salting period, 'Tuogu' plums lost 14.9 % of their moisture, compared to 'Bingtang' plums' 24.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Orthopaedic Surgery, Keck School of Medicine, Stem Cell Research and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA.
Interleukin-6 (IL-6) is a major pro-inflammatory cytokine that demonstrates a robust correlation with age and body mass index (BMI) as part of the senescence-associated secretory phenotype. IL-6 cytokines also play a crucial role in metabolic homeostasis and regenerative processes primarily via the canonical STAT3 pathway. Thus, selective modulation of IL-6 signaling may offer a unique opportunity for therapeutic interventions.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Skin aging is a multifaceted condition marked by the development of wrinkles, reduced suppleness, and uneven pigmentation. Both endogenous and exogenous factors contribute to skin aging. Studies have examined the possible anti-aging advantages of horsetail and soybean extracts, which are abundant in antioxidants.
View Article and Find Full Text PDFJ Craniofac Surg
October 2024
Department of Plastic and Cosmetic, Zhejiang Hospital, No.12 Lingyin Road, Xihu District, Hangzhou City, PR China.
With the growing demand for aesthetic enhancements, particularly filler injections for nasolabial folds (NLFs), there is a need for more objective and quantitative assessment methods beyond the traditional subjective scales like the Wrinkle Severity Rating Scale (WSRS). This study introduces a novel evaluation method combining 3-dimensional (3D) imaging and grayscale analysis to objectively assess NLF severity and treatment outcomes. A total of 100 healthy participants (86 females, 14 males; mean age 41.
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