AI Article Synopsis
- This study aimed to highlight the importance of conducting routine eye exams for newborns diagnosed with congenital cytomegalovirus (CMV) infection during their initial days.
- Researchers analyzed a group of 91 neonates with confirmed congenital CMV and found that most (79.12%) showed various symptoms, but no ocular issues were detected among them.
- The findings suggest that routine eye screenings for these infants may not be necessary right after birth and could be postponed until after the neonatal period.
Article Abstract
Purpose: To establish the clinical necessity of routine targeted ophthalmic examination of newborns with congenital cytomegalovirus (CMV) infection during the neonatal period.
Methods: This retrospective study included consecutive neonates that were referred for ophthalmological screening within the context of a proven congenital CMV infection. The presence of CMV-related ocular and systemic findings was determined.
Results: Among the 91 patients included in this study, 72 (79.12%) were symptomatic with one or more of the following manifestations: abnormal brain ultrasound (42; 46.15%), small for gestational age (29; 31.87%), microcephaly (23; 25.27%), thrombocytopenia (14; 15.38%), sensory neural hearing loss (13; 14.29%), neutropenia (12; 13.19%), anemia (4; 4.4%), skin lesions (4; 4.4%), hepatomegaly (3; 3.3%), splenomegaly (3; 3.3%), direct hyperbilirubinemia (2; 2.2%). Not one single neonate in this cohort had any of the ocular findings surveyed.
Conclusion: The presence of ophthalmological findings among neonates with congenital CMV infection during the neonatal period is infrequent, suggesting that routine ophthalmological screening may be safely deferred for the post-neonatal period.
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| http://dx.doi.org/10.1007/s10792-023-02775-2 | DOI Listing |
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