The effect of physical training on +Gz tolerance is of vital interest in the aerospace community. The data on the effect of physical training on orthostatic tolerance or simulated air combat maneuvers is equivocal. The effects of aerobic and strength training programs is briefly reviewed. The data suggest a need for careful reinterpretation of research results in light of conflicting reports and methodological shortcomings. Aerobic training cannot be assumed to always be detrimental nor can strength training be assumed to be universally effective in improving +Gz tolerance. In selecting appropriate screening criteria and training regimens for aircraft personnel, it seems prudent to reinvestigate strength and endurance training effects on +Gz tolerance using multivariate research paradigms. Special attention should be directed to commonly accepted physiological principles which may vary under conditions of altered gravitation.
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Front Med (Lausanne)
December 2024
Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Objective: To investigate the probability of hepatocellular carcinoma (HCC) in a large number of gray-zone (GZ) patients with chronic hepatitis B (CHB) in clinical practice.
Methods: The patients with CHB who were diagnosed and treated in our hospital from January 2013 to January 2023 were analyzed retrospectively.
Results: According to the different levels of HBeAg, ALT and HBV DNA, GZ patients were divided into four categories: (1) Gray zone A (GZ-A): HBeAg positive, normal ALT level, HBV DNA ≤ 10 IU/ml; (2) Gray zone B (GZ-B): HBeAg positive, ALT>ULN, HBV DNA ≤ 2 × 10 IU/ml; (3) Gray zone C (GZ-C): HBeAg negative, normal ALT level, HBV DNA ≥ 2 × 10 IU/ml; and (4) Gray zone D (GZ-D): HBeAg negative, ALT > ULN, serum HBV DNA ≤ 2 × 10 IU/ml.
BMJ Open
January 2025
Institute of Diabetes Research, Helmholtz Munich German Research Center for Environmental Health, Munich, Germany
Introduction: The identification of type 1 diabetes at an early presymptomatic stage has clinical benefits. These include a reduced risk of diabetic ketoacidosis (DKA) at the clinical manifestation of the disease and a significant reduction in clinical symptoms. The European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception (EDENT1FI) represents a pioneering effort to advance early detection of type 1 diabetes through public health screening.
View Article and Find Full Text PDFIntroduction: During centrifuge-simulated suborbital spaceplane flights, launch and re-entry frequently cause visual symptoms, and G-induced loss of consciousness can occur. G-related effects may be more prominent during re-entry from microgravity on actual flights. A modified anti-G maneuver that does not involve a breath strain and is suitable for members of the public may be effective against these effects.
View Article and Find Full Text PDFaBIOTECH
December 2024
State Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081 China.
Unlabelled: Sorghum, the fifth largest global cereal crop, comprises various types, such as grain, sweet, forage, and biomass sorghum, delineated by their designated end uses. Among these, sweet sorghum ( (L.) Moench) stands out for its unique versatility, exceptional abiotic stress tolerance and large biomass serving the multi-purpose of high-sugar forage, syrup, and biofuel production.
View Article and Find Full Text PDFBackground: Current HIV prophylactic vaccines evaluate HIV Env as purified proteins. CD40.HIVRI.
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