The objective of the study was to confirm the presence of different morphological forms of Leishmania infantum promastigotes on bone marrow aspirates from a Spanish Greyhound with canine leishmaniosis.
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- In areas where canine leishmaniosis is common, the non-pathogenic Leishmania tarentolae coexists with the harmful Leishmania infantum, raising questions about their interactions and potential immune responses in dogs.
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Lipophosphoglycan (LPG) is an important virulence factor. It is the most abundant surface glycoconjugate in promastigotes, playing an important role in the interaction with phagocytic cells. While LPG is known to modulate the macrophage immune response during infection, the activation mechanisms triggered by this glycoconjugate have not been fully elucidated.
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