Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335431 | PMC |
http://dx.doi.org/10.1136/bcr-2023-255049 | DOI Listing |
Nihon Shokakibyo Gakkai Zasshi
January 2025
Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine.
A 78-year-old male patient came to our hospital with a chief complaint of fever. Computed tomography revealed an indistinct tumor in the pancreatic head, along with dilatation of the bile duct and main pancreatic duct. An endoscopic transpapillary biopsy demonstrated adenocarcinoma in the glandular epithelium and a dense formation of quasi-round cells.
View Article and Find Full Text PDFLancet Gastroenterol Hepatol
February 2025
School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Pancreas Translational and Clinical Research Centre, Pancreatic and Transplant Surgery Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Eur J Endocrinol
January 2025
Department of Internal Medicine IV, LMU University Hospital, LMU Munich, 80336 Munich, Germany.
Objective: The effects of sex hormones remain largely unexplored in pheochromocytomas and paragangliomas (PPGLs) and gastroenteropancreatic neuroendocrine tumors (GEP-NETs).
Methods: We evaluated the effects of estradiol, progesterone, Dehydroepiandrosterone sulfate (DHEAS), and testosterone on human patient-derived PPGL/GEP-NET primary culture cell viability (n = 38/n = 12), performed next-generation sequencing and immunohistochemical hormone receptor analysis in patient-derived PPGL tumor tissues (n = 36).
Results: In PPGLs, estradiol and progesterone (1 µm) demonstrated overall significant antitumor effects with the strongest efficacy in PPGLs with NF1 (cluster 2) pathogenic variants.
Pigment Cell Melanoma Res
January 2025
Dermatology Research Centre, Frazer Institute, The University of Queensland, Brisbane, Australia.
Beta-blockers have generated an exciting discourse for their potential as a cheap, safe, and effective adjunctive therapy for cutaneous melanoma patients, but the field remains murky. This systematic review investigates the association between beta-blocker use and survival outcomes in cutaneous melanoma patients. We reviewed 12 studies with 21,582 patients in a network meta-analysis and found a benefit between beta-blocker use and disease-free survival but no other significant association for melanoma-specific or overall survival.
View Article and Find Full Text PDFKhirurgiia (Mosk)
January 2025
Medsi Clinical Hospital in Otradnoye of the Joint-Stock Company "Medsi Group of Companies", Krasnogorsk, Russia.
Unlabelled: The purpose of the study: to evaluate the impact of a comprehensive rehabilitation program on physical health indicators, such as weight restoration and improvement of functional capabilities of patients, psychoemotional state of patients, reduction of complications after surgical treatment.
Material And Methods: Observations were conducted on 148 patients diagnosed with melanoma of various localizations, who were divided into two groups by simple randomization: study (=77) and control (=71). The study group received surgical treatment in combination with rehabilitation programs (psychotherapy, nutritional support, general magnetic therapy), while the control group received only standard surgical treatment.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!