Capsicum peppers-including chili peppers, paprika, and red peppers-are native to the Americas but used worldwide in spicy dishes. Capsaicin, the active ingredient of Capsicum peppers, is used topically to treat musculoskeletal pain, neuropathy, and other conditions. Capsaicin binds the transient receptor potential vanilloid 1 (TRPV1), releasing substance P and desensitizing nerves with long-term use. Capsicum peppers and capsaicin products (eg, medications, cosmetics, pepper sprays) can provoke an irritant contact dermatitis, causing erythema and cutaneous burning. Capsaicin-induced dermatitis can be relieved by washing the area with soap, detergents, or oily compounds. Ice water or high-potency topical steroids also can help. Capsaicin is available in creams, lotions, and patches. Synthetic TRPV1-agonist injectables based on capsaicin are in clinical trials for use in localized pain. Capsaicin is a neuropeptide-active compound found in Capsicum peppers with many promising applications; however, dermatologists should be aware of possible skin reactions to these plants and medications derived from them.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.12788/cutis.0761 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Eco-Friendly Synthesis of Selenium Nanoparticles via Sternbergia candida: Enhancing Antioxidant Defense and Mitigating Salt Stress in Pepper (Capsicum annuum L.) Plants.
ChemistryOpen
January 2025
Department of Food Processing, Vocational School of Technical Science, 72060, Batman, Türkiye.
Nanoparticles enhance agricultural applications with their bioactivity, bioavailability, and reactivity. Selenium mitigates the adverse effects of salinity on plant growth, boosting antioxidant defense, metabolism, and resilience to abiotic stress. Our study applied selenium nanoparticles to mitigate salinity-induced damage and support plant growth.
View Article and Find Full Text PDFTransposon proliferation drives genome architecture and regulatory evolution in wild and domesticated peppers.
Nat Plants
January 2025
State Key Laboratory of Vegetable Biobreeding, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops of the Ministry of Agriculture and Rural Affairs, Sino-Dutch Joint Laboratory of Horticultural Genomics, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Pepper (Capsicum spp.) is a widely consumed vegetable with exceptionally large genomes in Solanaceae, yet its genomic evolutionary history remains largely unknown. Here we present 11 high-quality Capsicum genome assemblies, including two gap-free genomes, covering four wild and all five domesticated pepper species.
View Article and Find Full Text PDFDevelopment of a handheld GPU-assisted DSC-TransNet model for the real-time classification of plant leaf disease using deep learning approach.
Sci Rep
January 2025
Amal Jyothi College of Engineering (Autonomous), Kanjirappally, Kerala, India.
In agriculture, promptly and accurately identifying leaf diseases is crucial for sustainable crop production. To address this requirement, this research introduces a hybrid deep learning model that combines the visual geometric group version 19 (VGG19) architecture features with the transformer encoder blocks. This fusion enables the accurate and précised real-time classification of leaf diseases affecting grape, bell pepper, and tomato plants.
View Article and Find Full Text PDFA comprehensive review on sustainable strategies for valorization of pepper waste and their potential application.
Compr Rev Food Sci Food Saf
January 2025
Department of Biotechnology, Manipur University, Canchipur, Imphal, Manipur, India.
Pepper is an economically important crop grown worldwide for consumption as a vegetable and spice. Much waste, including crop plant waste, seeds, stalks, placenta, peels, and other processing byproducts, is generated by consumers during pepper crop production, processing, retail, and households. These peppers byproducts contain numerous bioactive compounds that can be used as ingredients for developing functional foods, nutraceuticals, and other food industries.
View Article and Find Full Text PDFBoosting Therapeutic Effect of Turmeric, Coffee, and Chili Extracts Through Experimental Design and Encapsulation as Nanostructured Lipid Carriers for Novel Heath Supplements.
Plants (Basel)
January 2025
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
This study investigates the potential synergistic effects of extracts from (turmeric), (Arabica coffee beans), and (chili peppers) in reducing oxidative stress and inflammation, which are associated with metabolic disorders such as obesity, diabetes, and cardiovascular diseases. Using a systematic design of experiment (DoE) optimization approach, an optimal extract ratio of 1:3:4 (turmeric: coffee: chili) was identified. The efficacy of the extract combination was assessed through various antioxidant assays, inhibition of inflammation-related gene expression, and safety testing via the 3-(4,5-dimethylthazolk-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!