Dynamic oxygen-17 (O) magnetic resonance imaging (MRI) is an imaging method that enables a direct and non-invasive assessment of cerebral oxygen metabolism and thus potentially the distinction between viable and non-viable tissue employing a three-phase inhalation experiment. The purpose of this investigation was the first application of dynamic O MRI at 7 Tesla (T) in a patient with stroke. In this proof-of-concept experiment, dynamic O MRI was applied during O inhalation in a patient with early subacute stroke. The analysis of the relative O water (HO) signal for the affected stroke region compared to the healthy contralateral side revealed no significant difference. However, the technical feasibility of O MRI has been demonstrated paving the way for future investigations in neurovascular diseases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317041 | PMC |
| http://dx.doi.org/10.3389/fnins.2023.1186558 | DOI Listing |
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