Melioidosis, a bacterial, infectious disease contracted from contaminated soil or water, is a public health problem identified in tropical regions and endemic several regions of Thailand. Surveillance and prevention are important for determining its distribution patterns and mapping its risk, which have been analysed in the present study. Case reports in Thailand were collected from 1 January 2016 to 31 December 2020. Spatial autocorrelation was analyzed using Moran's I and univariate local Moran's I. Spatial point data of melioidosis incidence were calculated, with riskmapping interpolation performed by Kriging. It was highest in 2016, at 32.37 cases per 100,000 people, and lowest in 2020, at 10.83 cases per 100,000 people. General observations revealed that its incidence decreased slightly from 2016 to 2018 and drastically in 2019 and 2020. The Moran's I values for melioidosis incidence exhibited a random spatial pattern in 2016 and clustered distribution from 2017 to 2020. The risk and variance maps show interval values. These findings may contribute to the monitoring and surveillance of melioidosis outbreaks.
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http://dx.doi.org/10.4081/gh.2023.1189 | DOI Listing |
Viruses
November 2024
Centre for Epidemiology and Planetary Health, School of Veterinary Medicine, Scotland's Rural College, Inverness IV2 5NA, UK.
Food contamination with non-typhoidal (NTS) presents a significant public health risk, underscoring the critical need for rigorous food safety measures throughout the production, distribution, preparation, and consumption stages. Conventional diagnostic strategies are time-consuming and labor-intensive and are thus sub-optimal for throughput NTS detection. Bacteriophages (phages) are highly specialized bacterial viruses and exhibit extreme specificity for their hosts.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
Department of Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Background: Melioidosis is a multisystem infectious disease caused by the environmental bacterium . Osteomyelitis (OM) and septic arthritis (SA) are uncommon primary presentations for melioidosis but important secondary foci, often requiring prolonged therapy and multiple surgeries. We characterized the epidemiology, presentation, treatment, and outcomes of patients from 24 years of the Darwin Prospective Melioidosis Study (DPMS).
View Article and Find Full Text PDFPLoS Negl Trop Dis
December 2024
Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America.
Background: Burkholderia pseudomallei, causative agent of melioidosis, is a One Health concern as it is acquired directly from soil and water and causes disease in humans and agricultural and wild animals. We examined B. pseudomallei in soil and goats at a single farm in the Northern Territory of Australia where >30 goats acquired melioidosis over nine years.
View Article and Find Full Text PDFInfect Med (Beijing)
December 2024
Department of Clinical Microbiology and Immunology, College of Pharmacy and Medical Laboratory, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Background: is a gram-negative bacterium widely found in Southeast Asia and northern Australia. This bacterium, which lacks an available vaccine, is the causative agent of melioidosis and has properties that potentially enable its exploitation as a bioweapon.
Methods: Polymerase chain reaction assays targeting each of the lipopolysaccharide (LPS) genetic types were used to investigate genotype frequencies in populations.
Open Forum Infect Dis
December 2024
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Respiratory viral infection may increase infection with progressing to clinical disease (melioidosis). This data linkage study evaluated associations between melioidosis and SARS-CoV-2 or influenza. Among 160 melioidosis cases, there was no difference in risk factors, vaccine status, or disease severity between 17 with viral co-infection and 143 without.
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