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Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972. | LitMetric
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Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972.

Ran Zhang Yujia Wang Guowei Cai Juxian Wang Jianyuan Zhao Jinglin Bai Tao Zhang Shan Cen Wenni He Liyan Yu

J Antibiot (Tokyo)

China Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.

Published: October 2023

There are six new phthalide derivatives Verbalide A ~ F (1-6) together with another known derivative (7) isolated from the endophytic fungus Preussia sp. CPCC 400972. Their structures were established by comprehensive spectroscopic analyses, including NMR and HRESIMS. In addition, compounds 1-7 exhibited excellent inhibitory effect against influenza A virus.

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http://dx.doi.org/10.1038/s41429-023-00640-zDOI Listing

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