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Ocular Metastatic Tumor in a Patient With Hepatocellular Carcinoma.
Cureus
November 2024
Surgery, Nippon Medical School, Tokyo, JPN.
While orbital floor metastasis from hepatocellular carcinoma (HCC) has been reported, ocular (eyeball) metastasis is exceedingly rare. Most ocular metastases originate from breast or lung cancer. In this article, we present the case of a 65-year-old man diagnosed with HCC with central necrosis (cT3N0M0, stage III) based on characteristic imaging findings.
View Article and Find Full Text PDFPneumothorax detection and segmentation from chest X-ray radiographs using a patch-based fully convolutional encoder-decoder network.
Front Radiol
December 2024
Computer Vision and Machine Intelligence Group, Department of Computer Science, University of the Philippines-Diliman, Quezon City, Philippines.
Pneumothorax, a life-threatening condition characterized by air accumulation in the pleural cavity, requires early and accurate detection for optimal patient outcomes. Chest X-ray radiographs are a common diagnostic tool due to their speed and affordability. However, detecting pneumothorax can be challenging for radiologists because the sole visual indicator is often a thin displaced pleural line.
View Article and Find Full Text PDFConcordance-based Predictive Uncertainty (CPU)-Index: Proof-of-concept with application towards improved specificity of lung cancers on low dose screening CT.
Artif Intell Med
December 2024
Department of Electrical and Computer Engineering, Duke University, Durham, NC, United States of America; Medical Physics Graduate Program, Duke University, Durham, NC, United States of America; Department of Radiology, Duke University, Durham, NC, United States of America; Department of Biomedical Engineering, Duke University, Durham, NC, United States of America; Department of Radiation Oncology, Duke University, Durham, NC, United States of America; Department of Pathology, Duke University, Durham, NC, United States of America. Electronic address:
In this paper, we introduce a novel concordance-based predictive uncertainty (CPU)-Index, which integrates insights from subgroup analysis and personalized AI time-to-event models. Through its application in refining lung cancer screening (LCS) predictions generated by an individualized AI time-to-event model trained with fused data of low dose CT (LDCT) radiomics with patient demographics, we demonstrate its effectiveness, resulting in improved risk assessment compared to the Lung CT Screening Reporting & Data System (Lung-RADS). Subgroup-based Lung-RADS faces challenges in representing individual variations and relies on a limited set of predefined characteristics, resulting in variable predictions.
View Article and Find Full Text PDFDual-layer dual-energy CT characterization of thrombus composition in acute pulmonary embolism and chronic thromboembolic pulmonary hypertension.
Int J Cardiovasc Imaging
December 2024
Department of Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
To evaluate dual-layer dual-energy computed tomography (dlDECT)-based characterization of thrombus composition for differentiation of acute pulmonary embolism (PE) and chronic thromboembolic pulmonary hypertension (CTEPH). This retrospective single center cohort study included 49 patients with acute PE and 33 patients with CTEPH who underwent CT pulmonary angiography on a dlDECT from 06/2016 to 06/2022. Conventional images), material specific images (virtual non-contrast [VNC], iodine density overlay [IDO], electron density [ED]), and virtual monoenergetic images (VMI) were analyzed.
View Article and Find Full Text PDFThe Spatial Distribution of Brain Metastasis Is Determined by the Heterogeneity of the Brain Microenvironment.
Hum Brain Mapp
December 2024
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
It is now understood that brain metastases do not occur randomly but have distinct spatial patterns depending on the origin of the cancer. According to the "seed and soil" hypothesis, the final colonization of metastatic cells is the result of their adaptation to the altered environment. To investigate the most favorable microenvironment for brain metastasis, we analyzed neuroimaging data from 177 patients with breast cancer brain metastasis and 548 patients with lung cancer brain metastasis to create a replicable probabilistic map of metastatic locations.
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