Intake and functional measurements of vitamin B6 were assessed for 40 institutionalized mentally retarded persons. Dietary intake was determined by observations during a 3-day period. Diets contained a mean of 1.6 mg/day of vitamin B6. The saturation of red cell aspartic transaminase was determined as a functional measurement of cellular B6 status. The mean saturation level did not differ significantly from a control group. There was a significant nonlinear correlation of intake and saturation level; 20% of the subjects fell below the level regarded as adequate. Although many of the subjects were receiving a variety of drugs, correlation of these data indicates that total intake of the vitamin accounted for most of the variability of the data. Protein and calorie intake were also examined.

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