AI Article Synopsis
- The glymphatic system is a network in the brain that helps deliver nutrients and remove waste using a pathway associated with specific proteins on astrocyte cells.
- This paper covers key aspects like the system's structure, how fluids and substances move within it, and the diseases that can affect its function.
- The authors aim to guide future research by summarizing important findings and methodologies related to the glymphatic system.
Article Abstract
The glymphatic system is a brain-wide perivascular pathway driven by aquaporin-4 on the endfeet of astrocytes, which can deliver nutrients and active substances to the brain parenchyma through periarterial cerebrospinal fluid (CSF) influx pathway and remove metabolic wastes through perivenous clearance routes. This paper summarizes the composition, overall fluid flow, solute transport, related diseases, affecting factors, and preclinical research methods of the glymphatic system. In doing so, we aim to provide direction and reference for more relevant researchers in the future.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308198 | PMC |
| http://dx.doi.org/10.3389/fnagi.2023.1179988 | DOI Listing |
Publication Analysis
Top Keywords
glymphatic system
12
system perspective
4
perspective brain
4
brain diseases
4
diseases glymphatic
4
system brain-wide
4
brain-wide perivascular
4
perivascular pathway
4
pathway driven
4
driven aquaporin-4
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!