Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11011-023-01261-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A3AR antagonism mitigates metabolic dysfunction-associated steatotic liver disease by exploiting monocyte-derived Kupffer cell necroptosis and inflammation resolution.
Metabolism
December 2024
College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, Chungbuk, South Korea. Electronic address:
Background & Aims: Metabolic dysfunction-associated steatotic liver (MASLD) progression is driven by chronic inflammation and fibrosis, largely influenced by Kupffer cell (KC) dynamics, particularly replenishment of pro-inflammatory monocyte-derived KCs (MoKCs) due to increased death of embryo-derived KCs. Adenosine A3 receptor (A3AR) plays a key role in regulating metabolism and immune responses, making it a promising therapeutic target. This study aimed to investigate the impact of selective A3AR antagonism for regulation of replenished MoKCs, thereby improving MASLD.
View Article and Find Full Text PDFAdjuvant Immunotherapy in High-Risk Muscle-Invasive Urothelial Cancer: An Updated Meta-Analysis of Randomized Controlled Trials.
Clin Genitourin Cancer
December 2024
Clion Clínica de Oncologia, Salvador, Bahia, Brazil.
Introduction: Neoadjuvant cisplatin-based chemotherapy followed by radical surgery is the standard treatment for muscle-invasive urothelial carcinoma (MIUC). The Checkmate-274 and AMBASSADOR trials have demonstrated improvements in disease-free survival (DFS) with adjuvant immunotherapy. Consequently, this meta-analysis aimed to assess the effectiveness of strategies involving checkpoint inhibitors in managing high-risk MIUC.
View Article and Find Full Text PDFMulti-scale temporal and spatial variations of soil heat flux under varying riparian forests: From a day to a year.
J Environ Manage
December 2024
School of Design, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address:
This study delves into the multi-scale temporal and spatial variations of soil heat flux (G) within riparian zones and its correlation with net radiation (Rn) across six riparian woodlands in Shanghai, each characterized by distinct vegetation types. The objective is to assess the complex interrelations between G and Rn, and how these relationships are influenced by varying vegetation and seasons. Over the course of a year, data on G and Rn is collected to investigate their dynamics.
View Article and Find Full Text PDFThe relationship between information literacy and online learning engagement: a moderated mediating model.
BMC Psychol
December 2024
Mental Health Education and Counseling Center, Nanchang Hangkong University, 696, Fenghe South Avenue, Nanchang, 330063, China.
Purpose: This study aims to examine how college students' information literacy affects their online learning engagement and what factors contribute to this relationship.
Method: The research adopted the method of cluster sampling to deliver a questionnaire survey to a sample of 1421 students' representative of four colleges. Information Literacy Scale, Online Learning Engagement Scale, Information Literacy Self-Efficacy Scale, and Psychological Resilience Scale were utilized in this study.
An improvised one-step OptiPrep cushion ultracentrifugation method for outer membrane vesicles isolation of Klebsiella pneumoniae.
BMC Microbiol
December 2024
Jiang Xi Hospital of China-Japan Friendship Hospital, Nanchang, Jiangxi, 330052, P.R. China.
Background: Extracellular vesicles (EVs) play a crucial role in intraspecies and interspecies communication, significantly influencing physiological and pathological processes. Outer membrane vesicles (OMVs) secreted by Gram-negative bacteria are rich in components from the parent cells and are important for bacterial communication, immune evasion, and pathogenic mechanisms. However, the extraction and purification of OMVs face numerous challenges due to their small size and heterogeneity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!