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Anticipatory smooth pursuit eye movements scale with the probability of visual motion: The role of target speed and acceleration.
J Vis
January 2025
Institut de Neurosciences de la Timone, CNRS & Aix-Marseille Université, Marseille, France.
Sensory-motor systems can extract statistical regularities in dynamic uncertain environments, enabling quicker responses and anticipatory behavior for expected events. Anticipatory smooth pursuit eye movements (aSP) have been observed in primates when the temporal and kinematic properties of a forthcoming visual moving target are fully or partially predictable. To investigate the nature of the internal model of target kinematics underlying aSP, we tested the effect of varying the target kinematics and its predictability.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Background: In this introductory talk, we embark on a journey of through the genomic frontiers of Alzheimer's research via the revolutionary Alzheimer's Disease Sequencing Project (ADSP).
Method: ADSP integrates together various components that collectively unravel the intricate genetic landscape of Alzheimer's disease with the ultimate goal of advancing precision medicine for the millions affected globally by this devastating disease. With a goal of sequencing and analyzing up to 150,000 complete genomes and associated clinical and functional data in the next five years, ADSP has amassed an unprecedented wealth of genomic data from diverse populations, providing a comprehensive and holistic understanding of the genetic underpinnings of Alzheimer's disease.
Background: We recently developed a novel tau-PET summary measure THETA, capturing regional heterogeneity and identifying tau status, using ground truth visual assessments from a large single-center cross-sectional dataset and validated on independent cohorts [1, 2]. In this study, we aimed to evaluate the performance of THETA on longitudinal and histopathology data.
Method: We included longitudinal tau-PET ([F]flortaucipir) data from 696 Mayo Clinic Study of Aging (MCSA) and ADRC participants, with histopathology in n = 90.
Human Footprint and Forest Disturbance Reduce Space Use of Brown Bears (Ursus arctos) Across Europe.
Glob Chang Biol
January 2025
Biotechnical Faculty, Department of Biology, University of Ljubljana, Ljubljana, Slovenia.
Three-quarters of the planet's land surface has been altered by humans, with consequences for animal ecology, movements and related ecosystem functioning. Species often occupy wide geographical ranges with contrasting human disturbance and environmental conditions, yet, limited data availability across species' ranges has constrained our understanding of how human pressure and resource availability jointly shape intraspecific variation of animal space use. Leveraging a unique dataset of 758 annual GPS movement trajectories from 375 brown bears (Ursus arctos) across the species' range in Europe, we investigated the effects of human pressure (i.
View Article and Find Full Text PDFClimate drives the long-term ant male production in a tropical community.
Sci Rep
January 2025
Grupo de Investigación Ecología y Evolución en los Trópicos-EETrop, Universidad de Las Américas, Quito, Ecuador.
Forecasting insect responses to environmental variables at local and global spatial scales remains a crucial task in Ecology. However, predicting future responses requires long-term datasets, which are rarely available for insects, especially in the tropics. From 2002 to 2017, we recorded male ant incidence of 155 ant species at ten malaise traps on the 50-ha ForestGEO plot in Barro Colorado Island.
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