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Zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis.
Biol Open
March 2025
Department of Pathology and Cell Biology, USF Health Heart Institute, University of South Florida, Tampa, FL 33602, USA.
During embryonic development vascular endothelial and hematopoietic cells are thought to originate from a common precursor, the hemangioblast. An evolutionarily conserved ETS transcription factor FLI1 has been previously implicated in the hemangioblast formation and hematopoietic and vascular development. However, its role in regulating hemangioblast transition into hematovascular lineages is still incompletely understood.
View Article and Find Full Text PDFTricuspid Annuloplasty Using a Handmade Gore-Tex Band: A Retrospective Study, Case Series, and Literature Review.
Cureus
March 2025
Division of Cardiac Surgery, University Hospital Center "Mother Teresa", Tirana, ALB.
Background Tricuspid valve regurgitation is frequently overlooked by cardiologists and cardiac surgeons alike; consequently, the tricuspid valve is often referred to as "the forgotten" valve. It is the most common complication of left heart valve disease. Ring annuloplasty and suture (De Vega) annuloplasty represent two common surgical treatment techniques.
View Article and Find Full Text PDFThe impact of temperature changes on the health vulnerability of migrant workers: an empirical study based on the China family panel studies.
Front Public Health
March 2025
School of Chinese Medicine, Hunan Brain Hospital, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Introduction: Migrant workers constitute a significant portion of China's workforce, and their health directly affects labor supply and economic stability. Health vulnerability plays a crucial role in shaping the well-being of migrant workers, yet its determinants, particularly the impact of temperature change, remain underexplored. This study, based on the socio-ecological model, investigates how temperature variations influence the health vulnerability of migrant workers in China.
View Article and Find Full Text PDFOpioid-Free Anesthesia for Upper Limb Surgery in Obese Patients as a Day Case Surgery: A Prospective Observational Study.
Anesth Pain Med
December 2024
Department of Anesthesiology, Faculty of Medicine, Fayoum University, Faiyum Governorate, Egypt.
Background: Opioid-free anesthesia (OFA) is a relatively new approach, and many studies are still needed to assess its effectiveness and compare it to opioid-based anesthesia (OBA).
Objectives: This study investigated the use of OFA in obese patients undergoing upper limb surgery and compares its outcomes with those of OBA.Methods:This prospective randomized clinical study included 76 obese patients with a Body Mass Index (BMI) ≥ 30 kg/m² who were scheduled for upper limb surgery.
Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer.
J Inflamm Res
March 2025
Department of Thoracic Surgery, The second People's Hospital of Changzhou, the Third Affiliated Hospital of Nanjing Medical University, Changzhou, 213164, People's Republic of China.
Background: Studies have demonstrated that histone deacetylase 1 () enables cancer cells to evade killing mediated by cytotoxic T lymphocytes. However, there are no studies on the immunological aspects of in non-small cell lung cancer (NSCLC).
Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate expression and prognosis in NSCLC.
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