[Primary-multiple cancer of the breast (from the data of the Chelyabinsk Regional Oncology Dispensary)].

102 cases of primary multiple breast cancer (bilateral and multicentric tumors-61; synchronous tumors of the breast and genitals-12) were treated at the Regional Oncological Dispensary in Chelyabinsk in 1976-83. Tumors generally occurred in patients of the 40-50 years bracket at an interval of 5.2 +/- 0.3 years. A certain role in the pathogenesis of primary multiple breast cancer was played by reproductive function as well as previous treatment modality (gamma-therapy, cytostatic treatment and ovariectomy).