AI Article Synopsis
- Taiwan has one of the highest rates of upper tract urothelial cancer (UTUC) in the world, especially among women, but there has been no comprehensive long-term study on this issue.
- A nationwide analysis of UTUC incidence from 1985 to 2019 used data from the Taiwan Cancer Registry, breaking down the population into nine age groups to assess age-specific trends.
- The findings revealed a notable increase in renal pelvis cancer incidence, with women experiencing a higher rise than men, particularly in older age groups and among younger cohorts compared to older ones.
Article Abstract
Background: Taiwan has one of the highest incidences of upper tract urothelial cancer (UTUC) worldwide, especially in women; however, no nationwide, long-term follow-up study has evaluated this.
Methods: We investigated the incidence of UTUC in Taiwan using data from the national population-based Taiwan Cancer Registry database (1985-2019). We divided the birth cohort into nine 5-year age groups and calculated the age-specific incidence for these groups according to the corresponding birth years.
Results: The average annual percent change in the incidence of renal pelvis cancer from 1985 to 2019 showed sex-specific differences, with 3.5% and 5.3% increases in the incidences in men and women, respectively. The age-specific incidence rate for renal pelvis cancer among women showed a gradual increase in the group with older women as well as an increase over time in each age group. The results of a birth cohort analysis revealed that younger cohorts had higher incidence rates of renal pelvis cancer than older cohorts did.
Conclusion: We demonstrated that the incidence of UTUC is unusually high among older Taiwanese women and that younger cohorts have a high risk of UTUC than older cohorts.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417072 | PMC |
| http://dx.doi.org/10.1002/cam4.6084 | DOI Listing |
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