Microplastics (MPs) are in all environmental compartments, including atmosphere, terrestrial, and aquatic environments as well as in marine organisms, foods, drinking water, and indoor and outdoor environments. MPs can enter the human body through the food chain and contaminated environment. Ingestion, inhalation, and dermal contact are the routes of their entry into the human body. Recent studies reporting the detection of MPs within the human body have raised concern among the scientific community as the knowledge about human exposure is still very limited and their impact on health is not well-understood yet. In this review article, we briefly cover the reports evidencing MP detection within the human body, e.g., stool, placenta, lungs, liver, sputum, breast milk, and blood. A concise synopsis of sample preparation and analysis of such human matrices is also provided. This article also presents a summary of the effect of MPs on human cell lines and human health.
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http://dx.doi.org/10.1016/j.etap.2023.104204 | DOI Listing |
Commun Psychol
January 2025
Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
How do people model the world's dynamics to guide mental simulation and evaluate choices? One prominent approach, the Successor Representation (SR), takes advantage of temporal abstraction of future states: by aggregating trajectory predictions over multiple timesteps, the brain can avoid the costs of iterative, multi-step mental simulation. Human behavior broadly shows signatures of such temporal abstraction, but finer-grained characterization of individuals' strategies and their dynamic adjustment remains an open question. We developed a task to measure SR usage during dynamic, trial-by-trial learning.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
January 2025
Faculty of Computer Science and Research Campus STIMULATE, Otto-von-Guericke University of Magdeburg, Magdeburg, Germany.
Purpose: Structured abdominal examination is an essential part of the medical curriculum and surgical training, requiring a blend of theory and practice from trainees. Current training methods, however, often do not provide adequate engagement, fail to address individual learning needs or do not cover rare diseases.
Methods: In this work, an application for structured Abdominal Examination Training using Augmented Reality (AETAR) is presented.
Sci Rep
January 2025
Department of Critical Care Medicine, Tongde Hospital of Zhejiang Province, #234 Gucui Road, Hangzhou, 310012, Zhejiang, People's Republic of China.
The intestinal barrier function is a critical defense mechanism in the human body, serving as both the primary target and initiating organ in cases of sepsis. Preserving the integrity of this barrier is essential for preventing complications and diseases, including sepsis and mortality. Despite this importance, the impact of resveratrol on intestinal barrier function remains unclear.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. Extrapolation of cell-type results to brain regions reveals the whole-brain impact of schizophrenia genetic risk, with subregions in the hippocampus and amygdala exhibiting the most significant enrichment of SNP-heritability.
View Article and Find Full Text PDFBMC Geriatr
January 2025
Institute of Health Promotion and Sport Sciences, Faculty of Education and Psychology, ELTE Eötvös Loránd University, Bogdánfy St. 12, Budapest, H-1117, Hungary.
Background: Physical fitness and functioning are related to better mental health in older age. However, which fitness components (body composition, strength, flexibility, coordination, and endurance) are more closely related to psychological well-being (PWB) is unclear.
Methods: This research examined how body mass index (BMI) and six indices of functional fitness (i.
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