Researchers frequently face ethical and privacy challenges on health applications. Ethics is a branch of moral philosophy and deals with the "right" and "good" actions of humans, which often leads to dilemmas. Reasons for this are social and societal dependencies of the respective norms. Data protection is regulated by law throughout Europe. This poster provides guidance on these challenges.
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Plagiarism in Publications: All about Being Fair!
Indian J Radiol Imaging
January 2025
Department of Radiology, Montefiore Health and Albert Einstein College of Medicine, Bronx, United States.
Upholding the highest standards of publication ethics is critical for ensuring the integrity of scholarly work, maintaining public trust, and advancing knowledge responsibly in academia. Plagiarism, defined as intellectual theft, is a significant ethical issue that undermines these principles. There are many forms of plagiarism, including direct, self, mosaic, and accidental plagiarism.
View Article and Find Full Text PDFGene therapy in polycystic kidney disease: A promising future.
J Transl Int Med
December 2024
Division of Nephrology, Shanghai Changzheng Hospital, Second Military Medical University (Naval Medical University), Shanghai 200003, China.
Polycystic kidney disease (PKD) is a genetic disorder marked by numerous cysts in the kidneys, progressively impairing renal function. It is classified into autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), with ADPKD being more common. Current treatments mainly focus on symptom relief and slowing disease progression, without offering a cure.
View Article and Find Full Text PDFDistance and Direction Matters: Risk Perception Among Residents Around a Dump Yard in Kerala, India.
Risk Manag Healthc Policy
January 2025
Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Purpose: Waste mismanagement is a growing concern in developing countries where unsustainable practices such as open dumping and open burning are rampant. This study examined the risk perceptions of the residents living in proximity to the Brahmapuram dump yard, situated in Ernakulam district of Kerala State, India- A site marked by persistent local protests, public outrage, and legal disputes arising from issues related to waste mismanagement. The study focused on the geospatial and sociodemographic factors that might influence these perceptions.
View Article and Find Full Text PDFValidation of a hypomorphic variant in CDK13 as the cause of CHDFIDD with autosomal recessive inheritance through determination of an episignature.
Clin Epigenetics
January 2025
Faculty of Medicine of TUD Dresden University of Technology, Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology, Dresden, Germany.
Autosomal dominant CDK13-related disease is characterized by congenital heart defects, dysmorphic facial features, and intellectual developmental disorder (CHDFIDD). Heterozygous pathogenic variants, particularly missense variants in the kinase domain, have previously been described as disease causing. Using the determination of a methylation pattern and comparison with an established episignature, we reveal the first hypomorphic variant in the kinase domain of CDK13, leading to a never before described autosomal recessive form of CHDFIDD in a boy with characteristic features.
View Article and Find Full Text PDFThe role of sleep quality in mediating the relationship between habenula volume and resilience.
Psychiatry Res
January 2025
Department of Neuropsychiatry, Graduate School of Medicine, Kyoto University, Japan; Artificial Intelligence Ethics and Society Team, RIKEN Center for Advanced Intelligence Project, Saitama, Japan; The General Research Division, Osaka University Research Center on Ethical, Legal and Social Issues, Kyoto, Japan. Electronic address:
Background: Our human volumetric MRI study (Dai et al., 2024) demonstrated that habenula (Hb) volume is associated with psychological resilience, a key protective factor against depression. However, the biological mechanisms underpinning this relationship remain unclear.
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