AI Article Synopsis
- Bariatric surgery helps in significant weight loss but can lead to nutrient deficiencies, necessitating supplementation.
- Researchers studied 85 adults post-surgery to assess changes in urinary iodine levels and thyroid function.
- Results showed an increase in urinary iodine concentration and a decrease in body mass index and thyroid stimulating hormone levels, confirming that surgery does not cause iodine deficiency or major thyroid function changes.
Article Abstract
Objective: Obesity has become an epidemic in the United States. Although bariatric surgery can effectively achieve weight loss by altering the gastrointestinal tract, it commonly results in micronutrient deficiency, requiring supplementation. Iodine is an essential micronutrient for the synthesis of thyroid hormones. We aimed to investigate changes in urinary iodine concentrations (UIC) in patients following bariatric surgery.
Methods: 85 adults who underwent either laparoscopic sleeve gastrectomy or laparoscopic Roux-en-Y gastric bypass surgery were enrolled. At baseline and 3 months after surgery, we evaluated spot UIC and serum thyroid stimulating hormone (TSH), vitamin D, vitamin B12, ferritin, and folate levels. Participants provided a 24-hour diet recall for iodine-rich foods and information about multivitamin use at each time point.
Results: There was a significant increase in median UIC (201 [120.0 - 288.5] vs 334.5 [236.3 - 740.3] μg/L; P < .001), a significant decrease in mean body mass index (44.0 ± 6.2 vs 35.8 ± 5.9; P < .001) and a significant decrease in TSH levels (1.5 [1.2 - 2.0] vs 1.1 [0.7 - 1.6] uIU/mL; P < .001) at 3 months postoperatively compared to baseline. Body mass index, UIC, and TSH levels before and after surgery did not differ based on the type of weight loss surgery.
Conclusion: In an iodine-sufficient area, bariatric surgery does not cause iodine deficiency nor clinically significant changes in thyroid function. Different surgical procedures with different anatomical alterations in the gastrointestinal tract do not significantly affect iodine status.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528999 | PMC |
| http://dx.doi.org/10.1016/j.eprac.2023.06.008 | DOI Listing |
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