Predicting and preventing heart failure in type 2 diabetes.

Lancet Diabetes Endocrinol

Division of Cardiac Surgery, St Michael's Hospital, University of Toronto, Toronto, ON, Canada. Electronic address:

Published: August 2023

AI Article Synopsis

  • * Understanding the underlying mechanisms and risk factors for heart failure in type 2 diabetes can help healthcare providers identify at-risk patients and enable earlier preventive interventions.
  • * The review also covers assessment tools for predicting heart failure risk, summarizes clinical trial data on lifestyle and medication interventions, and addresses challenges in managing these conditions with practical recommendations.

Article Abstract

The burden of heart failure among people with type 2 diabetes is increasing globally. People with comorbid type 2 diabetes and heart failure often have worse outcomes than those with only one of these conditions-eg, higher hospitalisation and mortality rates. Therefore, it is essential to implement optimal heart failure prevention strategies for people with type 2 diabetes. A detailed understanding of the pathophysiology underlying the occurrence of heart failure in type 2 diabetes can aid clinicians in identifying relevant risk factors and lead to early interventions that can help prevent heart failure. In this Review, we discuss the pathophysiology and risk factors of heart failure in type 2 diabetes. We also review the risk assessment tools for predicting heart failure incidence in people with type 2 diabetes as well as the data from clinical trials that have assessed the efficacy of lifestyle and pharmacological interventions. Finally, we discuss the potential challenges in implementing new management approaches and offer pragmatic recommendations to help overcome these challenges.

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Source
http://dx.doi.org/10.1016/S2213-8587(23)00128-6DOI Listing

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