Complications after Nephron-sparing Interventions for Renal Tumors: Imaging Findings and Management.

Radiographics

From the Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md (A.C., N.G., W.M.L., M.W.B.); Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Dr 1C352, Bethesda, MD 20892 (S.S., F.H., E.C.J., A.A.M.); and Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (P.B.S.).

Published: July 2023

AI Article Synopsis

  • The main kidney cancer treatments include surgical partial nephrectomy (PN) and image-guided percutaneous thermal ablation, both of which aim to minimize damage to kidney tissue.
  • Despite being effective, PN carries potential complications, like vascular injuries and urinary leaks, influenced by factors like tumor location and surgeon skill.
  • In contrast, percutaneous renal ablation has emerged as a safe alternative for small tumors, offering similar outcomes to PN with fewer serious complications, while requiring radiologists to recognize imaging indicators of potential issues post-procedure.

Article Abstract

The two primary nephron-sparing interventions for treating renal masses such as renal cell carcinoma are surgical partial nephrectomy (PN) and image-guided percutaneous thermal ablation. Nephron-sparing surgery, such as PN, has been the standard of care for treating many localized renal masses. Although uncommon, complications resulting from PN can range from asymptomatic and mild to symptomatic and life-threatening. These complications include vascular injuries such as hematoma, pseudoaneurysm, arteriovenous fistula, and/or renal ischemia; injury to the collecting system causing urinary leak; infection; and tumor recurrence. The incidence of complications after any nephron-sparing surgery depends on many factors, such as the proximity of the tumor to blood vessels or the collecting system, the skill or experience of the surgeon, and patient-specific factors. More recently, image-guided percutaneous renal ablation has emerged as a safe and effective treatment option for small renal tumors, with comparable oncologic outcomes to those of PN and a low incidence of major complications. Radiologists must be familiar with the imaging findings encountered after these surgical and image-guided procedures, especially those indicative of complications. The authors review cross-sectional imaging characteristics of complications after PN and image-guided thermal ablation of kidney tumors and highlight the respective management strategies, ranging from clinical observation to interventions such as angioembolization or repeat surgery. and Quiz questions for this article are available in the Online Learning Center. See the invited commentary by Chung and Raman in this issue.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323228PMC
http://dx.doi.org/10.1148/rg.220196DOI Listing

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