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Long-term follow-up of congenital hydronephrosis in a single-center study.
Int J Urol
May 2024
Department of Urology, Nara Medical University, Kashihara, Nara, Japan.
Objectives: Many congenital hydronephroses spontaneously resolve. This study evaluated a long-term follow-up of more than 4 years of patients with congenital hydronephrosis at a single center.
Methods: In total, 215 patients (286 kidneys) with congenital hydronephrosis were included.
Continence management in children with severe caudal regression syndrome: role of multidisciplinary team and long-term follow-up.
Pediatr Surg Int
October 2022
Division of Neuro-Urology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Purpose: Caudal regression syndrome (CRS) is a rare congenital abnormality including orthopedic deformities, urological, anorectal, and cardiac malformations. The clinical spectrum of CRS varies in severity, therefore multiple surgeries and complex medical care may be required with the efforts and support of a multidisciplinary team to ensure the most accurate treatment and the best outcome. The aim of our retrospective study was to evaluate the role of a multidisciplinary treatment and the long-term outcome in patients with severe CRS.
View Article and Find Full Text PDFA knock-in rat model unravels acute and chronic renal toxicity in glutaric aciduria type I.
Mol Genet Metab
December 2021
Pediatric Metabolic Unit, Pediatrics, Woman-Mother-Child Department, University of Lausanne and University Hospital of Lausanne, Switzerland. Electronic address:
Glutaric aciduria type I (GA-I, OMIM # 231670) is an autosomal recessive inborn error of metabolism caused by deficiency of the mitochondrial enzyme glutaryl-CoA dehydrogenase (GCDH). The principal clinical manifestation in GA-I patients is striatal injury most often triggered by catabolic stress. Early diagnosis by newborn screening programs improved survival and reduced striatal damage in GA-I patients.
View Article and Find Full Text PDFDoes relative renal function improve after intervention for chronic ureteric obstruction?
Cent European J Urol
February 2021
Institute of Urology, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Introduction: Unilateral renal function often deteriorates with chronic ureteric obstruction. Our objectives were to determine the change in relative renal function (RRF) by MAG3 renography after intervention for ureteric obstruction, and to identify clinical/epidemiological factors which influence long-term outcomes.
Material And Methods: We identified 228 patients from 2006 to 2017 who underwent MAG3 renography before and after intervention for unilateral ureteric obstruction.
Quality of Life of Patients After Laparoscopic Pyeloplasty Due to Ureteropelvic Junction Obstruction: A Long-Term Observation.
Adv Exp Med Biol
November 2021
Department of Urology, Fourth Military Hospital, Wroclaw, Poland.
Article Synopsis
- This study assesses the quality of life (QoL) of 26 patients who underwent laparoscopic pyeloplasty for ureteropelvic junction obstruction, with an average follow-up of 7.5 years.
- The assessment involved the World Health Organization Quality of Life (WHOQOL-BREF) questionnaire and a custom questionnaire focused on health-related QoL post-surgery.
- Results showed 96% patient satisfaction, with all but one patient content with treatment outcomes; the sole dissatisfaction was linked to ongoing pain, which did not significantly impact QoL for most patients.
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