A highly virulent sub-lineage of the M1 clone has been rapidly expanding throughout Denmark since late 2022 and now accounts for 30% of the new invasive group A streptococcal infections. We aimed to investigate whether a shift in variant composition can account for the high incidence rates observed over winter 2022/23, or if these are better explained by the impact of COVID-19-related restrictions on population immunity and carriage of group A .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311951PMC
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.26.2300291DOI Listing

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