A peculiar case of pure intraventricular glioblastoma.

Neurol Sci

IRCCS Institute of Neurological Sciences of Bologna, Division of Neurosurgery, Bellaria Hospital, via Altura 3, 40139, Bologna, Italy.

Published: October 2023

Glioblastoma (formerly named glioblastoma multiforme) is the most common primary central nervous system tumor, representing 45% of all cases and 15% of all intracranial neoplasms [1]. Its typical radiologic findings and localization make it often a lesion easy to diagnose. In MRI it usually appears as an irregularly shaped cystic lesion with ring contrast enhancement in T1-weighted images, localized in subcortical white matter and deep gray matter nuclei of the cerebral hemispheres. It involves more frequently the frontotemporal region followed by parietal lobes [1]. Few articles in literature described cases of intraventricular glioblastomas, defining those as secondary ventricular tumors because of their probable origin primarily from cerebral tissue with consequent transependymal development [2, 3]. Atypical presentations of these tumors make it more difficult to clearly differentiate them from other lesions more commonly located in the ventricular system. We describe a case with a unique radiological presentation: an intraventricular glioblastoma lying entirely within the ventricular walls, involving all the ventricular system, without mass effect or nodular parenchymal lesions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495531PMC
http://dx.doi.org/10.1007/s10072-023-06924-4DOI Listing

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