An active cloaking strategy for the scalar Helmholtz equation in three dimensions is developed by placing active sources at the vertices of Platonic solids. In each case, a "silent zone" is created interior to the Platonic solid and only the incident field remains in a defined region exterior to this zone. This distribution of sources ensures that implementation of the cloaking strategy is efficient: once the multipole source amplitudes at a single source location are determined, the other amplitudes are calculated by multiplying the multipole source vector by a rotation matrix. The technique is relevant to any scalar wave field.
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http://dx.doi.org/10.1121/10.0019906 | DOI Listing |
Drug Deliv Transl Res
January 2025
Department of Bioengineering, Indian Institute of Science, Bengaluru, 560012, India.
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View Article and Find Full Text PDFBig Data
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Department of Engineering Management, University of Antwerp, Antwerp, Belgium.
Our online lives generate a wealth of behavioral records--which are stored and leveraged by technology platforms. These data can be used to create value for users by personalizing services. At the same time, however, it also poses a threat to people's privacy by offering a highly intimate window into their private traits (e.
View Article and Find Full Text PDFMol Pharm
January 2025
Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Developing low-toxicity, high-efficacy, and fast-acting strategies to manage acute liver injury (ALI) is critical due to its rapid progression and potential for severe outcomes. Curcumin (CUR) has shown promise in ALI therapy due to its ability to modulate the inflammatory microenvironment by scavenging reactive oxygen species (ROS). Nevertheless, CUR is highly hydrophobic limiting its bioavailability and effective in vivo transport, which hinders its further application.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Key Laboratory of Organosilicon Chemistry and Materials Technology of Ministry of Education, College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, 311121 Hangzhou, P. R. China.
The integration of theranostics, which combines diagnostics with therapeutics, has markedly improved the early detection of diseases, precise medication management, and assessment of treatment outcomes. In the realm of oncology, organoplatinum-based supramolecular coordination complexes (SCCs) that can coload therapeutic agents and imaging molecules have emerged as promising candidates for multimodal theranostics of tumors. To address the challenges of tumor-targeted delivery and multimodal theranostics for SCCs, this study employs a cell membrane cloaking strategy to fabricate biomimetic metallacage nanoparticles (MCNPs) with multimodal imaging capabilities and homologous targeting capabilities.
View Article and Find Full Text PDFJ Colloid Interface Sci
March 2025
Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Física de Partículas, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain. Electronic address:
This investigation demonstrates the development and functionality of cell membrane-cloaked UiO-67 nanosized metal-organic frameworks (NMOFs), which are engineered for precise intracellular delivery of encapsulated cargoes. Utilizing the robust and porous nature of UiO-67, we enveloped these NMOFs with fusogenic cell membrane-derived nanovesicles (FCSMs) sourced from adenocarcinomic human alveolar basal epithelial (A549) cells. This biomimetic coating enhances biocompatibility and leverages the homotypic targeting capabilities of the cell-derived coatings, facilitating direct cytoplasmic delivery and avoiding endolysosomal entrapment.
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