[Epidemiologic characteristics and influencing factors of influenza outbreaks in Guangdong Province, 2015-2022].

To grasp the epidemiological characteristics of influenza outbreaks in Guangdong Province by analyzing the outbreaks of influenza-like cases reported in Guangdong Province from January 2015 to the end of August 2022. In response to the outbreak of epidemics in Guangdong Province from 2015 to 2022, information on on-site epidemic control was collected, and epidemiological analysis was conducted to describe the characteristics of the epidemics. The factors that influence the intensity and duration of the outbreak were determined through a logistic regression model. A total of 1 901 influenza outbreaks were reported in Guangdong Province, with an overall incidence of 2.05%. Most outbreak reports occurred from November to January of the following year (50.24%, 955/1 901) and from April to June (29.88%, 568/1 901). A total of 59.23% (1 126/1 901) of the outbreaks were reported in the Pearl River Delta region, and primary and secondary schools were the main places where outbreaks occurred (88.01%, 1 673/1 901). Outbreaks with 10-29 cases were the most common (66.18%, 1 258/1 901), and most outbreaks lasted less than seven days (50.93%,906/1 779). The size of the outbreak was related to the nursery school (a=0.38, 95%:0.15-0.93), the Pearl River Delta region (a=0.60, 95%:0.44-0.83), the time interval between the onset of the first case and the time of report (>7 days compared with ≤3 days: a=3.01, 95%:1.84-4.90), the influenza A(H1N1) (a=2.02, 95%:1.15-3.55) and the influenza B (Yamagata) (a=2.94, 95%: 1.50-5.76). The duration of outbreaks was related to school closures (a=0.65, 95%: 0.47-0.89), the Pearl River Delta region (a=0.65, 95%: 0.50-0.83) and the time interval between the onset of the first case and the time of report (>7 days compared with ≤3 days: a=13.33, 95%: 8.80-20.19; 4-7 days compared with ≤3 days: a=2.56, 95%: 1.81-3.61). An influenza outbreak in Guangdong Province exhibits two peaks, one in the winter and spring seasons and the other in the summer. Primary and secondary schools are high-risk areas, and early reporting of outbreaks is critical for controlling influenza outbreaks in schools. Furthermore, comprehensive measures should be taken to prevent the spread of the epidemic.