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Precision nutrition-based interventions for the management of obesity in children and adolescents up to the age of 19 years.
Cochrane Database Syst Rev
January 2025
Cornell Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, Ithaca, NY, USA.
Background: Precision nutrition-based methods develop tailored interventions and/or recommendations accounting for determinants of intra- and inter-individual variation in response to the same diet, compared to current 'one-size-fits-all' population-level approaches. Determinants may include genetics, current dietary habits and eating patterns, circadian rhythms, health status, gut microbiome, socioeconomic and psychosocial characteristics, and physical activity. In this systematic review, we examined the evidence base for the effect of interventions based on precision nutrition approaches on overweight and obesity in children and adolescents to help inform future research and global guidelines.
View Article and Find Full Text PDFOpenMS WebApps: Building User-Friendly Solutions for MS Analysis.
J Proteome Res
January 2025
Applied Bioinformatics, Department of Computer Science, University of Tübingen, Tübingen 72074, Germany.
Liquid chromatography-mass spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be challenging for nonexperts. To address this, we have developed OpenMS WebApps, a framework for creating user-friendly MS web applications based on the Streamlit Python package.
View Article and Find Full Text PDFSporadic and Recurrent Exertional Rhabdomyolysis.
Vet Clin North Am Equine Pract
January 2025
Michigan State University, Large Animal Clinical Sciences, College of Veterinary Medicine, East Lansing, MI, USA. Electronic address:
Horses are particularly susceptible to developing exertional rhabdomyolysis (ER) characterized by muscle stiffness, pain, and reluctance to move. Diagnosis requires establishing abnormal increases in serum creatine kinase activity when horses exhibit clinical signs. The 2 main categories of ER include sporadic ER arising from extrinsic causes and chronic ER that arises from intrinsic continuous or episodic abnormalities in muscle function.
View Article and Find Full Text PDFOtolaryngological manifestations of cystic fibrosis in children: A systematic review.
Int J Pediatr Otorhinolaryngol
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium; Department of Translational Neuroscience, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium. Electronic address:
Purpose: Cystic fibrosis (CF) is the most common autosomal recessive disorder in the Caucasian population. Otolaryngological manifestations pose a significant impact on the quality of life of children with CF. The primary aim of this review is to provide a state of the art update of current literature on the otolaryngological manifestations of CF in children.
View Article and Find Full Text PDFMftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.
Elife
January 2025
Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Mycofactocin is a redox cofactor essential for the alcohol metabolism of mycobacteria. While the biosynthesis of mycofactocin is well established, the gene , which encodes an oxidoreductase of the glucose-methanol-choline superfamily, remained functionally uncharacterized. Here, we show that MftG enzymes are almost exclusively found in genomes containing mycofactocin biosynthetic genes and are present in 75% of organisms harboring these genes.
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