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A prospective study to evaluate high dose daptomycin pharmacokinetics and pharmacodynamics in spp. infective endocarditis.
Ther Adv Infect Dis
January 2025
Clinica di Malattie Infettive, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy.
Background: Daptomycin pharmacokinetics and pharmacodynamics data relative to higher doses in patients are necessary for clinical practice.
Objectives: A monocentric, prospective study that enrolled patients with a diagnosis of spp. infective endocarditis treated with daptomycin according to clinical practice, to evaluate the pharmacokinetics/pharmacodynamics of different daptomycin daily doses (group A: 8-10 and group B: 11-12 mg/kg).
Role of the New Physical Examination Minor Criterion (New Heart Murmur) for the Diagnosis of Infective Endocarditis.
Open Forum Infect Dis
January 2025
Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Among 3127 episodes of suspected infective endocarditis, the 2023 Duke-International Society for Cardiovascular Infectious Diseases clinical criteria showed an accuracy of 90% for infective endocarditis diagnosis. A new heart murmur was present in 690 (22%) episodes. Excluding imaging and surgical findings decreased the accuracy to 73%, while using the physical examination criterion slightly improved the accuracy to 78%.
View Article and Find Full Text PDFRevisiting Ethical Considerations in Recurrent Injection Drug Use-Related Infective Endocarditis.
Ann Thorac Surg Short Rep
June 2023
Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Infective endocarditis caused by - a retrospective registry-based study.
Infect Dis (Lond)
January 2025
Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Purpose: Infective endocarditis (IE) is diagnosed using the Duke criteria, which were updated in 2023. In the Duke-ISCVID 2023 criteria, was recognised as a typical IE pathogen. This study investigates the impact of this change and compares the clinical characteristics of IE to IE caused by other pathogens.
View Article and Find Full Text PDFSafety and efficacy of the automated suture system in valvular heart surgery: a multicenter, prospective registry.
J Cardiovasc Surg (Torino)
December 2024
Department of Cardiovascular and Thoracic Surgery, Dijon University Hospital, Dijon, France.
Background: In the last years, the Cor-Knot device has been increasingly used in heart valve surgery. Our aim was to investigate the incidence of valvular complications in patients who underwent valvular surgery using the Cor-Knot device in multicentric cohorts at one-year follow-up.
Methods: Three hundred and sixty-eight patient underwent heart valve repair or replacement surgery using automated titanium suture fasteners in four cardiothoracic surgery departments between September 2018 and January 2020.
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