Background Temporomandibular joint ankylosis is a severe debilitating clinical condition where there is fusion of the mandible with the temporal bone. It is often a challenge to the maxillofacial surgeon as the surgical treatment protocol must be tailored individually according to the time of presentation of the ankylosis, and proper postoperative aggressive physiotherapy must be advocated, which is essential for a successful outcome. This is a case series of six recurrent temporomandibular joint ankylosis, in which the historical Esmarch surgery was done, and the pterygomassetric sling was interposed between the osteotomized segments. Postoperative mouth opening and surgical outcome were satisfactory. In our cases, we created a pseudojoint, which was very successful using the Esmarch procedure. Aim We aim to improve mouth opening in patients presenting with temporomandibular joint reankylosis using the Esmarch procedure and evaluate the efficacy of the conventional and modified Esmarch procedure. Materials and methods We have included six cases of recurrent temporomandibular joint reankylosis. Five cases were operated on using the conventional Esmarch procedure in which the osteotomy was done at the angle region, below the inferior alveolar nerve canal, and one case using the modified Esmarch procedure, wherein the osteotomy was done above the inferior alveolar nerve canal. The patients included in the case series presented with temporomandibular joint reankylosis and had undergone multiple surgeries for the release of ankylosis. Results Satisfactory postoperative mouth opening was achieved in all six patients. It was observed that in the modified Esmarch osteotomy, where the cuts were placed above the inferior alveolar nerve canal, there was a massive hemorrhage intraoperatively. This was primarily attributed to the altered anatomy of the maxillary artery, which was very close to the ankylotic mass. When the osteotomy was done below the inferior alveolar nerve canal, it was found that by this technique, the intraoperative hemorrhage was minimal, but it carries a risk of postoperative inferior alveolar nerve paresthesia, which was managed conservatively. Conclusion With the abovementioned results, we proceeded with the conventional Esmarch procedure for five cases and the modified Esmarch procedure for one case. It was found that in temporomandibular joint reankylosis cases, where there is extensive ankylotic mass extending from the glenoid fossa to the coronoid process of the mandible, this Esmarch procedure provides promising results when the osteotomy cuts are placed below the nerve canal.
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http://dx.doi.org/10.7759/cureus.39137 | DOI Listing |
Pathologie (Heidelb)
December 2024
Dermatologikum Hamburg, Stephansplatz 5, 20354, Hamburg, Deutschland.
Numerous diagnostic clues are used in routine dermatopathological diagnostics. Ideally, a diagnostic clue can lead directly to a specific diagnosis and save further time-consuming additional diagnostic procedures. This article discusses the concept of "clues to diagnosis" starting from its historical beginnings with a review of relevant studies and including current literature.
View Article and Find Full Text PDFBiomacromolecules
November 2024
Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz 55128, Germany.
Nanocarrier synthesis is highly process-dependent, leading to potential batch-to-batch variability if it is not controlled at each step. This variability affects the reproducibility of subsequent biomodification, resulting in unpredictable biological effects, particularly for bioactive molecules such as interleukin-2 (IL-2). Inconsistent conjugation can lead to variable treatment outcomes and severe side effects.
View Article and Find Full Text PDFDermatologie (Heidelb)
November 2024
Klinik für Hautkrankheiten, Universitätsklinikum Münster (UKM), Von-Esmarch-Str. 58, 48149, Münster, Deutschland.
Int J Mol Sci
August 2024
Core Facility Transgenic Animal and Genetic Engineering Models (TRAM), Medical Faculty, University of Münster, von-Esmarch str. 56, D-48149 Münster, Germany.
Determining the estrous cycle stages in mice is essential for optimizing breeding strategies, synchronizing experimental timelines, and facilitating studies in behavior, drug testing, and genetics. It is critical for reducing the production of genetically unmodified offspring in the generation and investigation of genetically modified animal models. An accurate detection of the estrus cycle is particularly relevant in the context of the 3Rs-Replacement, Reduction, and Refinement.
View Article and Find Full Text PDFNucl Med Commun
November 2024
Department of Orthopedics, Cixi People Hospital Medical Health Group (Cixi People Hospital), Zhejiang, China.
Objective: The objective of this study is to compare the effectiveness of the Esmarch bandage and exsanguination tourniquet rings (ETRs) in blood evacuation procedures using a controlled intra-subject design involving healthy volunteers.
Methods: A total of 20 healthy adult volunteers (12 males, 8 females) were recruited from the community. Participants underwent blood evacuation procedures on both legs, using the Esmarch bandage on one leg and the ETR on the other.
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