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| http://dx.doi.org/10.3762/bjoc.19.66 | DOI Listing |
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Department of Chemistry, University of Copenhagen, DK-2100, Copenhagen Ø, Denmark. Electronic address:
During a synthesis of the well-known and useful building block 6-hexa-O-tert-butyldimethylsilyl α-cyclodextrin (2) by silylation of α-cyclodextrin (1) we isolated as a byproduct the oversilylated 2,6-hepta-O-tert-butyldimethylsilyl α-cyclodextrin (3) where one 2-OH group has also been silylated. This unsymmetrical new compound has a remarkable H NMR spectrum in CDCl where all 11 alcohol groups are visible. We have analyzed the spectrum of 3 using 1D and 2D 800 MHz NMR and are able to assign all the 11 alcohol protons.
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