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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292641PMC
http://dx.doi.org/10.1093/omcr/omad058DOI Listing

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In this case, the patient had uterine adenocarcinoma with a huge necrotic mass prolapsed from the vagina, complicated by necrotic infection and massive bleeding. Based on ultrasound results preoperatively, uterine prolapse with infected necrosis was considered due to significant vaginal bleeding, prompting emergency surgery and blood transfusion. Postoperatively, pathology review indicated a misdiagnosis.

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Leuprolide acetate is commonly used to reduce the size of myomas before surgery. Initially, it stimulates pituitary gonadotropin secretion, followed by sustained suppression of gonadal function. However, the impact on pregnancy outcomes from inadvertent exposure remains unclear.

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The circRNA Landscape in Recurrent Pregnacy Loss (RPL): A Comparison of Four Reproductive Tissues.

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November 2024

Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena auzoa, 48940 Leioa, Spain.

Recurrent Pregnancy Loss (RPL), also named Recurrent Spontaneous Abortion (RSA), is a common fertility problem that refers to at least two consecutive pregnancy losses and affects 1-2% of couples all over the world. Despite common causes such as genetic abnormalities, uterine anomalies or hormonal and metabolic disorders, there is still a huge challenge in identifying the causes of about 40-60% of RPL patients. Circular RNAs (circRNAs) are endogenous ncRNAs with a unique closed-loop and single-stranded structure.

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A woman in her early 20s presented with a huge pedunculated tumour of the vulva which had progressively increased in size over the course of 10 years. Clinical examination revealed a pedunculated solid mass arising from the right labia majora measuring 15×15 cm. CT scan showed a multilobulated mass arising from the right round ligament suggestive of an extrauterine fibroid.

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  • - Cervical cancer is a major global health issue, particularly affecting women, and nurses caring for these patients face significant emotional challenges due to advanced stages of the disease and high caregiving demands.
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