AI Article Synopsis
- The gut microbiota plays a crucial role in a host's nutrition, immunity, and metabolism, and its imbalance (dysbiosis) is linked to various diseases.
- Fecal microbiota transplantation (FMT) is particularly effective in treating recurrent Clostridium difficile infections and is being explored for its potential benefits in other conditions, like inflammatory bowel diseases and cancers.
- Recent research highlights the promising role of FMT in managing cancer and its treatment-related complications, based on both preclinical and clinical evidence.
Article Abstract
In a mutually beneficial connection with its host, the gut microbiota affects the host's nutrition, immunity, and metabolism. An increasing number of studies have shown links between certain types of disease and gut dysbiosis or specific microorganisms. Fecal microbiota transplantation (FMT) is strongly advised for the treatment of recurrent or resistant Clostridium difficile infection (CDI) due to its outstanding clinical effectiveness against CDI. The therapeutic potential of FMT for other disorders, particularly inflammatory bowel diseases and malignancies, is currently gaining more and more attention. We summarized the most recent preclinical and clinical evidence to show the promise of FMT in the management of cancer as well as complications related to cancer treatment after reviewing the most recent research on the gut microbiota and its relationship to cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302701 | PMC |
| http://dx.doi.org/10.3390/pathogens12060766 | DOI Listing |
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