AI Article Synopsis
- The vaginal microbiota is essential for female reproductive health, influencing gynecological disorders and infertility.
- Lactobacilli are key beneficial bacteria, producing substances that inhibit harmful microorganisms and maintain a balanced environment.
- This review discusses how factors like hormonal changes and antibiotic use can disrupt vaginal health, affecting Assisted Reproductive Technology (ART) outcomes, and suggests strategies to restore a healthy microbiota.
Article Abstract
The vaginal microbiota plays a critical role in the health of the female genital tract, and its composition contributes to gynecological disorders and infertility. Lactobacilli are the dominant species in the female genital tract: their production of lactic acid, hydrogen peroxide, and bacteriocins prevents the invasion and growth of pathogenic microorganisms. Several factors such as hormonal changes, age of reproduction, sexual practices, menstrual cycle, pregnancy, and antimicrobial drugs use can cause imbalance and dysbiosis of the vaginal microbiota. This review aims to highlight the impact of the vaginal microbiota in Assisted Reproductive Technology techniques (ART) and it examines the factors that influence the vaginal microbiota, the consequences of dysbiosis, and potential interventions to restore a healthy female genital tract.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302789 | PMC |
| http://dx.doi.org/10.3390/microorganisms11061443 | DOI Listing |
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