Titanium alloy is a crucial structural material in the modern aerospace field due to its strong corrosion resistance and strength, low density, and reduced sensitivity to vibration load and impact load, as well as its ability to resist expansion in the case of cracks. However, during high-speed cutting of titanium alloy, it is prone to periodic saw-tooth chip formation, which can cause high-frequency fluctuations in the cutting force, aggravate the vibration of the machine tool system, and ultimately reduce the tool's service life and the workpiece's surface quality. In this study, we investigated the influence of the material constitutive law in modeling the Ti-6AL-4V saw-tooth chip formation and proposed a joint material constitutive law JC-TANH which was developed based on the Johnson-Cook constitutive law and the TANH constitutive law. It has two advantages of the two models (JC law and TANH law), which means that it can describe the dynamic properties accurately, the same as the JC model, not only under low strain but also under high strain. The most important thing is that it does not need to fit the JC curve at the early stage of strain changes. Additionally, we established a developed cutting model, which integrates the new material constitutive, and the improved SPH method to predict chip morphology, cutting and thrust forces which are collected by the force sensor; we also compared the data with experimental results. Experimental results show that this developed cutting model can better explain the shear localized saw-tooth chip formation and correctly estimate its morphology as well as the cutting forces.
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http://dx.doi.org/10.3390/ma16124465 | DOI Listing |
Math Mech Solids
January 2025
McMaster University, Hamilton, ON, Canada.
This paper deals with mesoscale analysis of masonry structures, which involves fracture propagation in brick units as well as along the masonry joints. The brick-mortar interfaces are incorporated in standard finite elements by employing a constitutive law with embedded discontinuity. Macrocracks in bricks are modelled in a discrete way using the same methodology, without any a-priori assumptions regarding their orientation.
View Article and Find Full Text PDFSci Rep
January 2025
Beijing Solidwel Intelligent Technology Co., Ltd., BeiJing, 100000, China.
Based on the Johnson-Cook constitutive model and modified Coulomb's law, the study investigates the impact of various process parameters on the weld temperature field in high-strength 5052 aluminum alloy friction stir welding (FSW) for aerospace applications. Utilizing a thermo-mechanical model, the significance of rotational speed, welding speed, and indentation on the peak weld temperature is examined through Taguchi's orthogonal experimental design. S/N ratio and ANOVA results show that the rotational speed has the most significant effect on the peak temperature of the weld, followed by the amount of indentation, and the welding speed has the smallest effect, the optimal combination of welding process parameters is determined as follows:the rotational speed is 1000 rpm, the amount of indentation is 0.
View Article and Find Full Text PDFParasit Vectors
December 2024
Institute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Background: Anthelmintic resistance in ruminants is a widespread problem that has a severe impact on productivity and animal welfare. The helminth Haemonchus contortus is generally considered the most important parasite in small ruminants due to its high pathogenicity and the widespread occurrence of anthelmintic resistance in it. Although the molecular mechanisms associated with resistance against the anthelmintics benzimidazoles (BZs) and levamisole are relatively well understood, the resistance mechanisms against the widely used anthelmintic macrocyclic lactones (MLs) ivermectin (IVM) and moxidectin (MOX) remain poorly understood.
View Article and Find Full Text PDFPLoS Negl Trop Dis
December 2024
Department of Health Law, Policy, & Management, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Climate-facilitated spread of mosquito-borne pathogens to new environments elevates the importance of policies that limit greenhouse gas emissions as well as the development and uptake of new pharmaceutical interventions. Whereas past research attempts to bolster support for both through either climate or health risk communication, fewer attempt to combine the risks borne by climate change and infectious disease with a single messaging intervention, i.e.
View Article and Find Full Text PDFBiochem J
December 2024
Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, U.S.A.
Conditions of endoplasmic reticulum (ER) stress reduce protein synthesis by provoking translation regulation, governed by the eIF2α kinase PERK. When PERK is inhibited during ER stress, retention of a selective subset of glycoproteins occurs, a phenomenon we termed selective ER retention (sERr). sERr clients are enriched with tyrosine kinase receptors (RTKs), which form large molecular weight disulfide bonded complexes in the ER.
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