AI Article Synopsis
- The study examines the effectiveness of minimally invasive surgical options, specifically laparoscopic ovarian drilling (LOD) and transvaginal hydrolaparoscopy (THL), for treating polycystic ovary syndrome (PCOS) in women who do not respond to medication and are trying to conceive.
- Analyzed data from 17 studies revealed that over 50% of women experienced spontaneous ovulation post-surgery, with a delivery rate exceeding 40%, particularly higher after LOD; however, there were instances of ectopic pregnancies and miscarriages reported.
- Overall, while evidence is limited and varied, the findings suggest that surgical interventions can be a viable and safe alternative for women with PCOS
Article Abstract
Objective: The surgical management of polycystic ovary syndrome (PCOS) represents an unclear option compared to medical therapy, and it is necessary to deepen the role of minimally invasive surgery, represented by laparoscopic ovarian drilling (LOD) and transvaginal hydrolaparoscopy (THL), for the treatment of PCOS in infertile women resistant to drug therapy and to establish its success in terms of ovulation and pregnancy rates.
Methods: A search was performed in the main electronic databases (MEDLINE, EMBASE, Web of Science, PubMed, and the Cochrane Library) from 1994 to October 2022 in order to evaluate the role of surgery in patients with PCOS resistant to pharmacological treatment. Only original scientific articles in English were included.
Results: Seventeen studies were analyzed in this review. In all analyzed studies, more than 50% of the population underwent spontaneous ovulation after surgical treatment without great differences between the two surgical techniques (LOD and THL). More than 40% of patients delivered, with a higher rate after LOD, although eight ectopic pregnancies and sixty-three miscarriages were reported. A lower risk of adhesion formation after THL has been reported. No clear data regarding the effect of surgery on the regularization of the menstrual cycle has been described. A reduction in LH and AMH serum levels as well as the LH/FSH ratio compared to preoperative levels for both surgical techniques has been described.
Conclusions: Despite the scarcity and heterogeneity of data, surgical therapy could be considered an effective and safe approach in the management of PCOS patients with resistance to pharmacological treatment who desire to become pregnant.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304625 | PMC |
| http://dx.doi.org/10.3390/life13061270 | DOI Listing |
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