Endocrine-disrupting chemicals (EDCs) are chemicals, either natural or synthetic, that can interfere with the production, distribution, function, metabolism, or excretion of hormones in our body [...].
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| http://dx.doi.org/10.3390/ijms24129790 | DOI Listing |
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Unveiling the silent defenders: mycobacterial stress sensors at the forefront to combat tuberculosis.
Crit Rev Biotechnol
January 2025
Department of Life Sciences, Shiv Nadar Institution of Eminence (Deemed to be University), Gautam Buddha Nagar, Uttar Pradesh, India.
The global escalation in tuberculosis (TB) cases accompanied by the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of ( emphasizes the critical requirement for novel potent drugs. The demonstrates extraordinary adaptability, thriving in diverse conditions, and always finds itself in win-win situations regardless of whether the environment is favorable or unfavorable; no matter the magnitude of the challenge, it can endure and survive. This review aims to uncover the role of multiple stress sensors of that assist bacteria in remaining viable within the host for years against various physiological stresses offered by the host.
View Article and Find Full Text PDFSelf-reported sexually transmitted infections and associated factors among sexually active men in East Africa: a multilevel analysis of recent demographic and health surveys.
BMJ Open
January 2025
Department of Public Health, Collage of Medicine and Health Sciences, Samara University, Samara, Ethiopia.
Background: Sexually transmitted infections (STIs) are a significant global health challenge, demanding attention and intervention. Despite many STIs being manageable, their asymptomatic nature poses a formidable threat to both mental and physical well-being. This silent impact can lead to substantial morbidity and mortality, which is particularly pronounced in East Africa.
View Article and Find Full Text PDFThe Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case.
Microorganisms
January 2025
Immunopharmacology Laboratory, Oswaldo Cruz Institute/FIOCRUZ, Rio de Janeiro 21040-361, RJ, Brazil.
Background: Human metapneumovirus (hMPV) is a respiratory pathogen that has gained increasing recognition due to advancements in molecular diagnostic tools, which have improved its detection and characterization. While severe disease manifestations are traditionally associated with pediatric, elderly, or immunocompromised patients, hMPV-related pneumonia in immunocompetent adults remains underexplored.
Methods: This case report describes a 68-year-old male who developed severe community-acquired pneumonia (CAP) caused by hMPV despite being immunocompetent and having no significant comorbidities.
Silent Carriers: The Hidden Threat of Antibiotic-Resistant in Retail Seafood Across Poland's Tri-City Area.
Antibiotics (Basel)
January 2025
Department of Quality Management, Faculty of Management and Quality Sciences, Gdynia Maritime University, 81-87 Morska St., 81-225 Gdynia, Poland.
: Antibiotic-resistant poses a significant risk to food safety and public health, particularly through the consumption of contaminated seafood. This study aimed to assess the presence and antibiotic resistance of in seafood sold in the Tri-City area of Poland, addressing a knowledge gap regarding the region. : Seafood samples ( = 89) were categorized according to their origin: domestic-Poland (PL), European countries (ECs), and Asian countries (ACs).
View Article and Find Full Text PDFA Silent Threat Unveiled: Mycobacterium gordonae Catheter-Related Peritonitis in a Patient on Peritoneal Dialysis.
Cureus
December 2024
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, THA.
Infectious complications in peritoneal dialysis (PD) remain a constant challenge, with atypical pathogens posing significant risks. This case from Thailand highlights the rare occurrence of , an often-overlooked non-tuberculous mycobacterium (NTM), as the causative agent in a catheter-related exit-site infection that progressed to peritonitis. Initially misattributed to from preceding exit-site infections, was ultimately identified as the primary pathogen through multiple effluent cultures and advance polymerase chain reaction sequencing.
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