When mood states are impaired, daily life is severely disrupted. To maintain a specific mood state, both positive and negative moods must be controlled; however, methods to maintain a positive mood have not been fully established. Previous studies have suggested that heat-killed MCC1848 has the potential to improve positive moods. This study aimed to test the efficacy of heat-killed MCC1848 in maintaining and improving a positive mood with PANAS, a questionnaire specifically designed to assess positive and negative mood, as the primary endpoint. Healthy Japanese nursing students ( = 46) were randomized to receive heat-killed MCC1848 (5 billion/day) or placebo powder for four weeks. Mood state was assessed before and two and four weeks after the intervention began; ingestion of heat-killed MCC1848 significantly improved PANAS 'Positive Affect' compared to the placebo. These results indicate that heat-killed MCC1848 is effective in enhancing positive mood.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296070 | PMC |
| http://dx.doi.org/10.3390/brainsci13060973 | DOI Listing |
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