Multiple Myeloma: Case of a "Moving" Sternal Wire.

Diagnostics (Basel)

Department of Diagnostic Imaging, National University Hospital, Singapore 119074, Singapore.

Published: June 2023

Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB features). A 64-year-old man with no history of malignancy presented with an enlarging precordial lump occurring three years post-sternotomy for uneventful coronary artery bypass grafting surgery. Initial investigations showed anaemia and impaired renal function. Multimodal imaging performed for further evaluation showcases the radio-pathological features which can be encountered in haematological malignancy. Subsequent percutaneous biopsy confirmed an underlying plasma cell neoplasm, and a diagnosis of multiple myeloma was achieved. The prompt resolution of the lesions upon the initiation of treatment highlights the importance of early diagnosis and treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297185PMC
http://dx.doi.org/10.3390/diagnostics13122082DOI Listing

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