Introduction: Damage to the nozzle tips of intraocular lens (IOL) injectors has been associated with various adverse events and even IOL surface abnormalities after IOL implantation. In this study, nozzle tip damage of three different injector models with v-notched nozzle tips was systematically evaluated using our self-developed system - the Heidelberg Score for IOL injector damage.

Methods: Nozzle tip damage was categorized into 6 grades: no damage (grade 0), slight scratches (1), deep scratches (2), extensions (3), cracks (4), and bursts (5). Each grade was assigned to a score of 0-5. In each IOL injector group, all IOLs were divided into 2 subgroups based on IOL power: +15 to +21D group and +21 to +26D group. The total scores for each group were the sum of scores for all injectors in this group. Further analysis was performed on the nozzle tip configuration and parameters in each injector model.

Results: The median (Q1-Q3) for each injector group in group +15 to +21D was 1.5 (1-2) for Avansee, 4 (3-4) for iSert, and 4 (3-4) for multiSert. A statistically significant difference was found between Avansee and iSert (p < 0.001) as well as between Avansee and multiSert (p < 0.01) in terms of median scores. The median (Q1-Q3) for each injector group in group +21 to +26D was 1.5 (1-2) for Avansee, 4 (4-4) for iSert, and 3 (3-3.75) for multiSert. A statistically significant difference was found between Avansee and iSert in terms of median scores (p < 0.001). The outer cross-sectional diameters were 1.80 and 1.78 mm for Avansee, 1.70 and 1.69 mm for iSert, and 1.69 and 1.68 mm for multiSert. The radii of each notch-based circle were 0.21 mm (Avansee), 0.09 (iSert), and 0.06 (multiSert), respectively. The tip angles for three injector models were 48° (Avansee), 46° (iSert), and 37° (multiSert).

Conclusions: Avansee showed the least nozzle tip damage of all three groups. Compared with our earlier study using preloaded injectors with intact endpieces, all the injector groups with v-notched nozzle tips had more damage to the nozzle tip. It was found that the closer the notch of the nozzle tip was to the letter "V," the more damaged the nozzle tip was after IOL implantation.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614508PMC
http://dx.doi.org/10.1159/000531078DOI Listing

Publication Analysis

Top Keywords

nozzle damage
16
nozzle tips
12
injector group
12
nozzle
10
group
9
avansee
9
intraocular lens
8
damage nozzle
8
iol implantation
8
damage three
8

Similar Publications

Glaucoma treatment involves reducing the intraocular pressure (IOP), which can damage the optic nerve, to a normal range. Aqueous drainage devices may be used for treatment, and a variety of devices have been proposed. However, they have a non-variable and uniform inner diameter, which makes it difficult to accommodate the IOP fluctuations that occur after glaucoma surgery.

View Article and Find Full Text PDF

Pneumatic conveying inkjet bioprinting for the processing of living cells.

Biofabrication

January 2025

Research Group Anatomy, School for Medicine and Health Science, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Str.9-11, Oldenburg, 26129, GERMANY.

Inkjet printing techniques are often used for bioprinting purposes because of their excellent printing characteristics, such as high cell viability and low apoptotic rate, contactless modus operandi, commercial availability, and low cost. However, they face some disadvantages, such as the use of bioinks of low viscosity, cell damage due to shear stress caused by drop ejection and jetting velocity, as well as a narrow range of available bioinks that still challenge the inkjet printing technology. New technological solutions are required to overcome these obstacles.

View Article and Find Full Text PDF

Study on the foam production characteristics of air self-suction foam generator by jet.

Sci Rep

January 2025

Key Laboratory of Gas and Fire Control for Mines, Ministry of Education, Xuzhou, 221116, China.

Confined space fires could easily cause serious casualties and property damage, and foam is an effective means of preventing confined space fires. The existing foam generator does not have both momentum and foam expansion rate (FER) and is poorly suited to confined spaces. In order to develop a foam generator suitable for confined space fire protection, an in-depth analysis of the physical foaming characteristics of self-suction foam is required, and the structure of the foam generator is optimized accordingly.

View Article and Find Full Text PDF

Background: A growing body of research is dedicated to developing new therapeutic agents for wound healing with fewer adverse effects. One of the proceedings being taken today in wound healing research is to identify promising biological materials that not only heal wounds but also vanish scarring. The effectiveness of nanofibers like polyvinyl alcohol (PVA), in improving wound healing can be related to their unique properties.

View Article and Find Full Text PDF

High-Pressure Injection Injuries of the Hand: A Report of Three Cases Presenting With Acute Compartment Syndrome.

Cureus

October 2024

Department of Plastic and Reconstructive Surgery and Burns Unit, Coimbra Local Health Unit, Coimbra, PRT.

Article Synopsis
  • High-pressure injection injuries in the hand often result from industrial tools like paint guns or air compressors, typically affecting laborers' non-dominant hands and causing damage that’s often underestimated despite appearing as a small puncture wound.
  • These injuries can cause severe complications such as neurovascular compromise and acute compartment syndrome due to the spread of injected materials that can be toxic and lead to further tissue damage or infections.
  • A presentation of three cases highlights urgent surgery needs for patients who experienced severe pain and swelling after different injected substances, leading to procedures for decompression, irrigation, and tissue removal to prevent serious outcomes.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!