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Bioimpedance analysis of fat free mass and its subcomponents and relative associations with maximal oxygen consumption in facioscapulohumeral dystrophy.
Eur J Appl Physiol
August 2024
CRIAMS-Sport Medicine Centre Voghera, University of Pavia, 27058, Voghera, Italy.
Purpose: Fat free mass (FFM) is considered the metabolically active component of human body and is positively associated with maximal oxygen uptake ( ). However, FFM is composed of metabolically active and inactive subcomponents whose proportion can vary depending on body composition and clinical condition, possibly affecting such association. Although it is known that in facioscapulohumeral dystrophy (FSHD) peculiar changes in body composition occur, it is unclear whether there are alterations in FFM composition and, if so, whether such alterations affect the association towards compared to healthy subjects (HS).
View Article and Find Full Text PDFNitrogen Reduction to Ammonia on a Fe Nanocluster: A Computational Study of Catalysis.
J Phys Chem A
November 2023
Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisiana 71272, United States.
The sequence of elementary steps leading to reductive ammonia formation from N and H catalyzed by a Fe cluster is studied using generalized gradient approximation density functional theory and an all-electron basis set of triple-ζ quality. The computational methods are validated by comparison to experimental data such as binding energies where possible. First, the associative and dissociative attachment of N to Fe is considered, followed by exploration of the pathways leading to distal (Fe-N-NH) and enzymatic (NFe-NH) formation of an amino group.
View Article and Find Full Text PDFNew Facet in Viscometry of Charged Associating Polymer Systems in Dilute Solutions.
Polymers (Basel)
February 2023
Institute of Macromolecular Compounds, Russian Academy of Sciences Bolshoi pr. 31, 199004 Saint Petersburg, Russia.
The peculiarities of viscosity data treatment for two series of polymer systems exhibiting associative properties: brush-like amphiphilic copolymers-charged alkylated N-methyl-N-vinylacetamide and N-methyl-N-vinylamine copolymer (MVAA--MVACH) and charged chains of sodium polystyrene-4-sulfonate (PSSNa) in large-scale molecular masses (MM) and in extreme-scale of the ionic strength of solutions were considered in this study. The interest in amphiphilic macromolecular systems is explained by the fact that they are considered as micellar-forming structures in aqueous solutions, and these structures are able to carry hydrophobic biologically active compounds. In the case of appearing the hydrophobic interactions, attention was paid to discussing convenient ways to extract the correct value of intrinsic viscosity η from the combined analysis of Kraemer and Huggins plots, which were considered as twin plots.
View Article and Find Full Text PDFStriatal topographical organization: Bridging the gap between molecules, connectivity and behavior.
Eur J Histochem
October 2021
Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina.
Article Synopsis
- The striatum is a crucial part of the basal ganglia, involved in complex behaviors and receiving input from the entire cerebral cortex, but its organization is still not fully understood.
- Research focuses on the striatum's anatomy at various scales to connect its structure with function and understand its role in neuropsychiatric disorders.
- Despite being divided into dorsal and ventral regions, the striatum exhibits functional diversity influenced by different histochemical features, neuronal gene expression patterns, and varied neurotransmitter connections.
Memories are not written in stone: Re-writing fear memories by means of non-invasive brain stimulation and optogenetic manipulations.
Neurosci Biobehav Rev
August 2021
IRCCS Fondazione Santa Lucia, 00179 Rome, Italy.
The acquisition of fear associative memory requires brain processes of coordinated neural activity within the amygdala, prefrontal cortex (PFC), hippocampus, thalamus and brainstem. After fear consolidation, a suppression of fear memory in the absence of danger is crucial to permit adaptive coping behavior. Acquisition and maintenance of fear extinction critically depend on amygdala-PFC projections.
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