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Local cytokine levels associate with SNOT-22 and UPSIT scores in chronic rhinosinusitis. | LitMetric

AI Article Synopsis

  • Elevated levels of IL-5, IL-13, IL-33, and CCL2 are linked to lower scores on the University of Pennsylvania Smell Identification Test (UPSIT) in patients with Chronic Rhinosinusitis (CRS) and Aspirin-Exacerbated Respiratory Disease (AERD).
  • Higher levels of IL-5, IL-13, TNF-α, CCL2, and CXCL-8 are associated with increased scores on the Sino-Nasal Outcome Test (SNOT-22) in the same patient populations.
  • These findings suggest a complex relationship between inflammatory markers and the severity of nasal symptoms and smell function in CRS and AERD patients.

Article Abstract

Elevated IL-5, IL-13, IL-33, and CCL2 correlate with lower UPSIT scores in CRS and AERD patients. Elevated IL-5, IL-13, TNF-α, CCL2, and CXCL-8 correlate with higher SNOT-22 scores in CRS and AERD patients.

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Source
http://dx.doi.org/10.1002/alr.23222DOI Listing

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