Background: Intestinal pseudo-obstruction (IPO) is a rare disease, and its clinical manifestations can resemble mechanical intestinal obstruction leading to unnecessary and potentially harmful surgery. Certain autoimmune diseases have been associated with IPO, however, cases secondary to Sjögren's syndrome (SjS) are especially rare.
Case Presentation: We described the first case of SjS-associated acute IPO in pregnancy, which was successfully treated with combined immunosuppressive therapy and resulted in an uneventful caesarean delivery.
Conclusions: Women with SjS is likely to experience more complications during pregnancy, and IPO rather than the classic symptoms could be the first sign of SjS flares. IPO should be suspected in patients with unrelenting symptoms of small bowel obstruction, and a multidisciplinary approach can provide optimal management of such high-risk pregnancies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294411 | PMC |
| http://dx.doi.org/10.1186/s12884-023-05757-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Utility of Monitoring Fasting Phase During Pediatric Colonic Manometry Studies.
Neurogastroenterol Motil
January 2025
Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Introduction: Colonic manometry (CM) is a diagnostic procedure used to evaluate pediatric patients with refractory constipation, fecal incontinence, Hirschsprung disease, and pediatric intestinal pseudo-obstruction. Pan-colonic high-amplitude propagated contractions (HAPCs), measured by CM, reflect an intact neuromuscular function of the colon. Current guidelines recommend starting CM with fasting recording for 1-2 h, but no prior evaluation has determined the diagnostic yield of the fasting phase.
View Article and Find Full Text PDFSurgical and Therapeutic Interventions for Chronic Intestinal Pseudo-obstruction: A Scoping Review.
J Neurogastroenterol Motil
January 2025
Departments of Gastroenterology and 3Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Background/aims: Chronic intestinal pseudo-obstruction (CIPO) is a rare cause of intestinal dysmotility. First-line treatment in adult patients is medical and nutritional therapy. For patients who fail these treatment options, surgical interventions may be an option.
View Article and Find Full Text PDFAnti-PD1-/PDL1-induced chronic intestinal pseudo-obstruction: three cases treated with vedolizumab after corticosteroid failure with mixed results.
Cancer Immunol Immunother
January 2025
Department of Medical Oncology, Institut de Cancérologie de L'Ouest, 44805, Saint Herblain, France.
Article Synopsis
- Immune checkpoint inhibitors (ICI) have transformed cancer treatment but can lead to rare and serious neurological side effects, such as chronic intestinal pseudo-obstruction (CIPO).
- CIPO may be linked to T cell infiltration and presents with vague symptoms like nausea and constipation, complicating diagnosis and treatment.
- In three cases treated with vedolizumab after corticosteroids failed, there was minimal improvement, suggesting vedolizumab is not an effective option for ICI-induced CIPO at this time.
Visible Peristalsis in a Patient Referred for Chronic Intestinal Pseudo-Obstruction.
Am J Gastroenterol
January 2025
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Ogilvie's Syndrome Following Herpes Zoster Infection: A Comprehensive Review of the Literature.
Cureus
November 2024
Department of General Surgery, Western General Hospital, Edinburgh, GBR.
This systematic review explores the association between herpes zoster (HZ) infection and Ogilvie's syndrome (acute colonic pseudo-obstruction), evaluating how varicella-zoster virus (VZV) reactivation may contribute to autonomic dysfunction leading to intestinal obstruction. A comprehensive search was conducted in PubMed, Scopus, and Cochrane Library databases up to October 2024, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies included case reports, clinical images, and letters reporting Ogilvie's syndrome secondary to HZ or VZV infection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!