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Cognitive impairment and dementia have long been recognized as growing public health threats. Studies have found that air pollution is a potential risk factor for dementia, but the literature remains inconclusive. This study aimed to evaluate the association between three major air pollutants (i.
View Article and Find Full Text PDFEffects of Gene-Lifestyle Interaction on Obesity Among Students.
Genes (Basel)
November 2024
Laboratory of Genetics of Aging and Longevity, Kazan State Medical University, 420012 Kazan, Russia.
Background: Obesity is a global health issue influenced primarily by genetic variants and environmental factors. This study aimed to examine the relationship between genetic and lifestyle factors and their interaction with obesity risk among university students.
Methods: A total of 658 students from the same university participated in this study, including 531 females (mean age (SD): 21.
Immunological memory in a teleost fish: common carp IgM B cells differentiate into memory and plasma cells.
Front Immunol
January 2025
Laboratory of Fish Protistology, Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czechia.
Article Synopsis
- All vertebrates, from ancient fishes to mammals, possess adaptive immunity and immunological memory, although the specific responding cells in fish have not been clearly defined.
- Researchers infected common carp with a cnidarian parasite and observed that B cells proliferated and showed signs of differentiation, indicating they can form memory cells.
- The study revealed that these memory B cells can persist for at least six months, alongside identifying a distinct population of plasma cells, suggesting that teleost fish possess the necessary immune components for effective long-term disease protection akin to other vertebrates.
The Interaction of Racial-Ethnic and Economic Concentration and its Association with Premature Mortality in U.S. Neighborhoods.
J Racial Ethn Health Disparities
January 2025
Center for Population Health Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Recent research shows a significant link between race-ethnicity and income concentration and premature death rates in the U.S. However, most studies focus on Black-White residential concentration, overlooking racial-ethnic diversity.
View Article and Find Full Text PDFProton Pump Inhibitor Use and Incident Cardiovascular Disease in Older Postmenopausal Women.
J Am Geriatr Soc
December 2024
Department of Epidemiology and Environmental Health, University at Buffalo - SUNY, Buffalo, New York, USA.
Background: Epidemiological studies have been inconsistent regarding an association between proton pump inhibitor (PPI) use and risk of primary cardiovascular disease (CVD) events.
Methods: We studied 85,189 postmenopausal women (mean age 63 years at baseline) without known CVD at enrollment into the Women's Health Initiative Observational Study (1993-1998). PPI use was determined from medication inventories at baseline and Year-3.
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