Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.plasmid.2023.102697 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
interspecies dissemination of IncM2-type carrying plasmid.
Microbiol Spectr
December 2024
National Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
The gastrointestinal tract is a unique ecological niche with a high abundance of various Enterobacterales in close proximity. This allows the exchange of mobile genetic elements that carry resistance determinants. In the hospital setting, resistant organisms are prevalent and selective antibiotic pressure is high, providing a supportive platform for interspecies dissemination of resistance.
View Article and Find Full Text PDFEukaryotes have linear DNA and their telomeres are hotspots for transposons, which in some cases took over telomere maintenance. While many bacteria also have linear chromosomes and plasmids, no transposons were known to target bacterial telomeres. Here we show several families of independently evolved telomeric transposons in cyanobacteria and .
View Article and Find Full Text PDFPolymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins.
Mol Biol Cell
November 2024
Department of Cellular and Molecular Pharmacology, UCSF, San Francisco 94158, CA.
Dynamically unstable polymers capture and move cellular cargos in bacteria and eukaryotes, but regulation of their assembly remains poorly understood. Here we describe polymerization of Alp7A, a bacterial actin-like protein (ALP) that distributes copies of plasmid pLS20 among daughter cells in . Purified ATP-Alp7A forms dynamically unstable polymers with a high critical concentration for net assembly (cc = 10.
View Article and Find Full Text PDFHeterogeneity in establishment of polyethylene glycol-mediated plasmid transformations for five forest pathogenic Phytophthora species.
PLoS One
September 2024
Department of Forest & Conservation Sciences, Faculty of Forestry, University of British Columbia, Vancouver, British Columbia, Canada.
Plasmid-mediated DNA transformation is a foundational molecular technique and the basis for most CRISPR-Cas9 gene editing systems. While plasmid transformations are well established for many agricultural Phytophthora pathogens, development of this technique in forest Phytophthoras is lacking. Given our long-term research objective to develop CRISPR-Cas9 gene editing in a forest pathogenic Phytophthora species, we sought to establish the functionality of polyethylene glycol (PEG)-mediated plasmid transformation in five species: P.
View Article and Find Full Text PDFImage-Guided Mesenchymal Stem Cell Sodium Iodide Symporter (NIS) Radionuclide Therapy for Glioblastoma.
Cancers (Basel)
August 2024
Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA.
Background: Glioblastoma (GBM) is a highly aggressive, invasive, and growth factor-independent grade IV glioma. Survival following the diagnosis is generally poor, with a median survival of approximately 15 months, and it is considered the most aggressive and lethal central nervous system tumor. Conventional treatments based on surgery, chemotherapy, and radiation therapy only delay progression, and death is inevitable.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!