Background: Surgery for hand trauma accounts for a significant proportion of the plastic surgery training curriculum. The aim of this article is to create a standardised simulation training module for hand fracture fixation on open reduction and internal fixation (ORIF) techniques for residents in order to create a standardised hand-training framework that universally hones their skill and prepares them for their first encounter in a clinical setting.
Methods: A step-ladder approach training using three-dimensional (3D)-printed ex vivo hand biomimetics was employed on a cohort of 15 plastic surgery residents ( = 15). Assessment of skills using a score system (global rating scale) was performed in the beginning and the end of the module by hand experts in our unit.
Results: The overall average score of the cohort pre- and post-assessment were 22.08/50 (44.16%) and 41.54/50 (83.08%) respectively. Significant ( < 0.01) difference of improvement of skills was noted on all trainees. All trainees confirmed that the simulated models provided in this module were akin to the patient scenario and noted that it helped them improve their skills with regards to ORIF techniques including improvement of their understanding of the 3D bone topography.
Conclusion: We demonstrate a standardised simulation training framework that employs 3D-printed ex vivo hand biomimetics proven to improve the skills of residents and which paves the way to more universal, standardised and validated training across hand surgery. This is, to our knowledge, the first standardised method of simulated training on such hand-surgical cases.Level of Evidence: Not ratable.
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http://dx.doi.org/10.1007/s00238-023-02062-4 | DOI Listing |
Lab Chip
January 2025
Nanobioelectronics Laboratory (NBEL), Department of Biomedical Engineering, Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501 Beer Sheva, Israel.
Dissolved oxygen is crucial for metabolism, growth, and other complex physiological and pathological processes; however, standard physiological models (such as organ-on-chip systems) often use ambient oxygen levels, which do not reflect the lower levels that are typically found . Additionally, the local generation of reactive oxygen species (ROS; a key factor in physiological systems) is often overlooked in biology-mimicking models. Here, we present a microfluidic system that integrates electrochemical dissolved oxygen sensors with lab-on-a-chip technology to monitor the physiological oxygen concentrations and generate hydrogen peroxide (HO; a specific ROS).
View Article and Find Full Text PDFACS Omega
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.
Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and the capacity to form arbitrarily complex structures. However, 3D printing alone is insufficient for manufacturing two-stage titanium implants due to the limited precision in printing titanium alloy parts.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun, China. Electronic address:
Promoting angiogenesis, alleviating oxidative stress injury and inflammation response are crucial for bone healing. Herein, the deferoxamine (DFO)-loaded gelatin methacryloyl (GelMA) hydrogel coating (GelMA-DFO) was constructed on the 3D-printed poly(Glycolide-Co-Caprolactone)-hydroxyapatite (PGCL-HAP) scaffold. After the hydrogel coating was established, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscope (SEM) and water contact angle measurement were employed to evaluate the characteristic and the biological properties were assessed.
View Article and Find Full Text PDFInt J Pharm
January 2025
Department of Stem Cells and Regenerative Medicine, D. Y. Patil Education Society (Deemed to be University), Kolhapur 416006, India. Electronic address:
Managing wounds and accompanying consequences like exudation and microbiological infections is challenging in clinical practice. Bioactive compounds from traditional medicinal plants help heal wounds, although their bioavailability is low. This study uses sodium alginate (SA), gelatin (G), and Santalum album oil (SAL) to 3D print a polymeric hydrogel scaffold to circumvent these difficulties.
View Article and Find Full Text PDFNat Commun
January 2025
Key Laboratory of Underwater Acoustic Communication and Marine Information Technology of the Ministry of Education, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China.
Aberration layers (AL) often present significant energy transmission barriers in microwave engineering, electromagnetic waves, and medical ultrasound. However, achieving broadband ultrasonic focusing through aberration layers like the human skull using conventional materials such as metals and elastomers has proven challenging. In this study, we introduce an inverse phase encoding method employing tunable soft metalens to penetrate heterogeneous aberration layers.
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